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2.3.1.286: protein acetyllysine N-acetyltransferase

This is an abbreviated version!
For detailed information about protein acetyllysine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.286

Reaction

[protein]-N6-acetyl-L-lysine
+
NAD+
 +
H2O
=
[protein]-L-lysine
 +
2''-O-acetyl-ADP-D-ribose
 +
nicotinamide

Synonyms

Af2Sir2, Clr3, CobB, HDAC, histone deacetylase, Hst1, HST2, Hst2p, KAT, More, NAD+-dependent protein deacetylase, NAD-dependent histone deacetylase, NAD-dependent protein deacetylase, nicotinamide adenine dinucleotide-dependent protein deacetylase, patZ, peptidyl-lysine N-acetyltransferase, phnO, protein lysine acetyltransferase, protein lysine deacetylase, Rv1151c, silent information regulator 2, Sir-2, Sir2, SIR2-Af1, Sir2-Af2, Sir2A, Sir2Af2, Sir2alpha, Sir2p, SIRT1, SIRT2, SIRT3, SIRT5, sirtuin, sirtuin 1, sirtuin 3, sirtuin-2 deacetylase, YfiQ, YiaC, YjaB

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.286 protein acetyllysine N-acetyltransferase

Cloned

Cloned on EC 2.3.1.286 - protein acetyllysine N-acetyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
a gene encoding the C-terminally His-tagged SIRT1 catalytic domain is expressed in SF9 cells
Q96EB6
expressed in Escherichia coli
-
expressed in Escherichia coli BL21 cells
expressed in Escherichia coli BL21(DE3) and B834 (DE3) cells
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3) CodonPlus RIPL cells
expressed in Escherichia coli Codon-plus RIPL cells
-
expressed in Escherichia coli XL1Blue cells
-
expressed in Mycobacterium smegmatis mc2155 cells
-
expressed in Sf9 insect cells
expression in Escherichia coli
gene patZ, sequence comparisons and phylogenetic analysis, recombinant enzyme overexpression in Escherichia coli strain BW25113
gene phnO, sequence comparisons and phylogenetic analysis, recombinant enzyme overexpression of wild-type and mutant enzymes in Escherichia coli strain BW25113
gene yiaC, sequence comparisons and phylogenetic analysis, recombinant enzyme overexpression of wild-type and mutant enzymes in Escherichia coli strain BW25113
gene yjaB, sequence comparisons and phylogenetic analysis, recombinant enzyme overexpression of wild-type and mutant enzymes in Escherichia coli strain BW25113
recombinant human SIRT2 (43-356) is expressed as a His-Sumo fusion protein in Escherichia coli
SIRT1-FL (full-length human SIRT1) is cloned in the pECE vector (clone 1791) and N-terminally truncated SIRT1 (SIRT1-NT with residues 7–83 deleted) cloned in the pCDNA3.1 vector. To express the FLAGtagged hSIRT1 (human SIRT1) proteins, the hSIRT1 constructs are transfected into HEK (human embryonic kidney)-293T cells
Q96EB6