1.14.14.94: leukotriene-B4 20-monooxygenase

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For detailed information about leukotriene-B4 20-monooxygenase, go to the full flat file.

Reaction

Synonyms

CYP4 omega-hydroxylase, CYP4A11, CYP4F11, CYP4F12, CYP4F13, CYP4F14, CYP4F15, CYP4F16, CYP4F17, CYP4F18, CYP4F2, CYP4F3, CYP4F37, CYP4F39, CYP4F3A, CYP4F3B, CYP4F4, CYP4F40, CYP4F8, CYPIVF2, CYPIVF3, cytochrome CYP4F3A, cytochrome P-450 4F18, cytochrome P450 4F2, cytochrome P450 4F3, Cytochrome P450-LTB-omega, EC 1.14.13.30, leukotriene B4 20-hydroxylase, leukotriene B4 omega-1/omega-2 hydroxylase, leukotriene B4 omega-hydroxylase, Leukotriene-B4 20-monooxygenase, leukotriene-B4 omega-hydroxylase, LTB4 20-hydroxylase, LTB4 hydroxylase, LTB4 omega hydroxylase, LTB4 omega-hydroxylase, LTB4OH, More, oxygenase, leukotriene B4 20-mono-, TOH-omega-hydroxylase, vitamin E-omega-hydroxylase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.14.94 leukotriene-B4 20-monooxygenase

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Results	in table
7	Activating Compound
25	AA Sequence
1	Application
1	CAS Registry Number
18	Cloned(Commentary)
7	Cofactor
446	Disease/ Diagnostics
4	Expression
4	General Information
16	Inhibitors
3	Ki Value [mM]
41	KM Value [mM]
16	Localization
2	Metals/Ions
6	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
36	Organism
3	Pathway
7	pH Optimum
1	pH Range
5	Protein Variants
5	Purification (Commentary)
2	Reaction
3	Reaction Type
32	Reference
65	Source Tissue
2	Specific Activity [micromol/min/mg]
5	Storage Stability
99	Substrates and Products (Substrate)
1	Subunits
75	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]

Purification

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Purification on EC 1.14.14.94 - leukotriene-B4 20-monooxygenase

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PURIFICATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

CYP4F3

Homo sapiens

-

660409

recombinant enzyme

Homo sapiens

-

658922

recombinant enzyme from insect Sf9 suspension cultures, to near homogeneity, native enzyme partially from liver and kidney by microsome preparation

Homo sapiens

-

684731

recombinant protein CYP4F2, expressed in yeast

Homo sapiens

-

390075

recombinant protein CYP4F3, expressed in yeast

Homo sapiens

-

390073