2.1.1.B130: [histone H3]-N-methyllysine9 N-methyltransferase
This is an abbreviated version!
For detailed information about [histone H3]-N-methyllysine9 N-methyltransferase, go to the full flat file.
Reaction
+ 2 S-adenosyl-L-methionine = + 2 S-adenosyl-L-homocysteine
Synonyms
SU(VAR)3-9 RELATED4, SUVR4
ECTree
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Engineering
Engineering on EC 2.1.1.B130 - [histone H3]-N-methyllysine9 N-methyltransferase
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A32E
mutation in WIYLD domain, reduces the binding affinity to ubiquitin by 37%. The mutation disrupts the entire domain structure
W61R
mutation in WIYLD domain, reduces the binding affinity to ubiquitin by 75%