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2.1.1.B130: [histone H3]-N-methyllysine9 N-methyltransferase

This is an abbreviated version!
For detailed information about [histone H3]-N-methyllysine9 N-methyltransferase, go to the full flat file.

Reaction

N6-methyl-L-lysyl9-[histone H3]
+ 2 S-adenosyl-L-methionine =
N6,N6,N6-trimethyl-L-lysyl9-[histone H3]
+ 2 S-adenosyl-L-homocysteine

Synonyms

SU(VAR)3-9 RELATED4, SUVR4

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.B130 [histone H3]-N-methyllysine9 N-methyltransferase

Activating Compound

Activating Compound on EC 2.1.1.B130 - [histone H3]-N-methyllysine9 N-methyltransferase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ubiquitin
addition of free ubiquitin stimulates enzymatic activity of the SUVR4 protein on histone H3 but does not affect its specificity. In presence of ubiquitin, methylation of H3K9me1 modified peptides increases 2.5-3fold. Trimethylation of the H3K9me2 peptide is observed in the presence of ubiquitin