2.1.1.B130: [histone H3]-N-methyllysine9 N-methyltransferase
This is an abbreviated version!
For detailed information about [histone H3]-N-methyllysine9 N-methyltransferase, go to the full flat file.
Reaction
+ 2 S-adenosyl-L-methionine = + 2 S-adenosyl-L-homocysteine
Synonyms
SU(VAR)3-9 RELATED4, SUVR4
ECTree
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Activating Compound
Activating Compound on EC 2.1.1.B130 - [histone H3]-N-methyllysine9 N-methyltransferase
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ubiquitin
addition of free ubiquitin stimulates enzymatic activity of the SUVR4 protein on histone H3 but does not affect its specificity. In presence of ubiquitin, methylation of H3K9me1 modified peptides increases 2.5-3fold. Trimethylation of the H3K9me2 peptide is observed in the presence of ubiquitin