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1.14.14.125: monacolin L hydroxylase

This is an abbreviated version!
For detailed information about monacolin L hydroxylase, go to the full flat file.

Reaction

monacolin L acid
+
O2
+
[reduced NADPH-hemoprotein reductase]
=
monacolin J acid
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

EC 1.14.13.198, LovA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.125 monacolin L hydroxylase

Systematic Name

Systematic Name on EC 1.14.14.125 - monacolin L hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
monacolin L acid,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
A cytochrome P-450 (heme-thiolate) protein. The enzyme from fungi also catalyses the reaction of EC 1.14.14.124, dihydromonacolin L hydroxylase.