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1.14.14.125: monacolin L hydroxylase

This is an abbreviated version!
For detailed information about monacolin L hydroxylase, go to the full flat file.

Reaction

monacolin L acid
+
O2
+
[reduced NADPH-hemoprotein reductase]
=
monacolin J acid
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

EC 1.14.13.198, LovA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.125 monacolin L hydroxylase

Cloned

Cloned on EC 1.14.14.125 - monacolin L hydroxylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
the lovA gene in C-terminal FLAG-tagged form is cloned in the same vector coding cpr (cytochrome P450 oxidoreductase), and both lovA and cpr are co-expressed in Saccharomyces cerevisiae