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1.14.19.60: 7-chloro-L-tryptophan 6-halogenase

This is an abbreviated version!
For detailed information about 7-chloro-L-tryptophan 6-halogenase, go to the full flat file.

Reaction

7-chloro-L-tryptophan
+
FADH2
+
chloride
+
O2
+
H+
=
6,7-dichloro-L-tryptophan
+
FAD
+ 2 H2O

Synonyms

KtzR

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.60 7-chloro-L-tryptophan 6-halogenase

Reference

Reference on EC 1.14.19.60 - 7-chloro-L-tryptophan 6-halogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Heemstra, J.R. Jr.; Walsh, C.T.
Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly
J. Am. Chem. Soc.
130
14024-14025
2008
Kutzneria sp. 744 (A8CF74)
Manually annotated by BRENDA team