1.1.1.430: D-xylose reductase (NADH)
This is an abbreviated version!
For detailed information about D-xylose reductase (NADH), go to the full flat file.
Reaction
Synonyms
CbXR, CT-XR, dsXR, NAD(P)H-dependent D-xylose reductase, NADH-dependent XR, NADPH-preferring xylose reductase, PsXR, XYL1, XYL1.1, XYL1.2, xylose reductase
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Reference
Reference on EC 1.1.1.430 - D-xylose reductase (NADH)
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Lee, J.K.; Koo, B.S.; Kim, S.Y.
Cloning and characterization of the xyl1 gene, encoding an NADH-preferring xylose reductase from Candida parapsilosis, and its functional expression in Candida tropicalis
Appl. Environ. Microbiol.
69
6179-6188
2003
Candida parapsilosis (Q6Y0Z3), Candida parapsilosis KFCC-10875 (Q6Y0Z3)
Nidetzky, B.; Klimacek, M.; Mayr, P.
Transient-state and steady-state kinetic studies of the mechanism of NADH-dependent aldehyde reduction catalyzed by xylose reductase from the yeast Candida tenuis
Biochemistry
40
10371-10381
2001
Yamadazyma tenuis
Petschacher, B.; Nidetzky, B.
Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae
Microb. Cell Fact.
7
9
2008
Yamadazyma tenuis
Khoury, G.A.; Fazelinia, H.; Chin, J.W.; Pantazes, R.J.; Cirino, P.C.; Maranas, C.D.
Computational design of Candida boidinii xylose reductase for altered cofactor specificity
Protein Sci.
18
2125-2138
2009
[Candida] boidinii
Pival, S.L.; Klimacek, M.; Nidetzky, B.
The catalytic mechanism of NADH-dependent reduction of 9,10-phenanthrenequinone by Candida tenuis xylose reductase reveals plasticity in an aldo-keto reductase active site
Biochem. J.
421
43-49
2009
Yamadazyma tenuis (O74237)
Krahulec, S.; Petschacher, B.; Wallner, M.; Longus, K.; Klimacek, M.; Nidetzky, B.
Fermentation of mixed glucose-xylose substrates by engineered strains of Saccharomyces cerevisiae: role of the coenzyme specificity of xylose reductase, and effect of glucose on xylose utilization
Microb. Cell Fact.
9
16
2010
Yamadazyma tenuis
Zhang, B.; Li, L.; Zhang, J.; Gao, X.; Wang, D.; Hong, J.
Improving ethanol and xylitol fermentation at elevated temperature through substitution of xylose reductase in Kluyveromyces marxianus
J. Ind. Microbiol. Biotechnol.
40
305-316
2013
Kluyveromyces marxianus, Kluyveromyces marxianus YHJ010
Weyda, I.; Luebeck, M.; Ahring, B.K.; Luebeck, P.S.
Point mutation of the xylose reductase (XR) gene reduces xylitol accumulation and increases citric acid production in Aspergillus carbonarius
J. Ind. Microbiol. Biotechnol.
41
733-739
2014
Aspergillus carbonarius, Aspergillus carbonarius ITEM 5010
Pratter, S.M.; Eixelsberger, T.; Nidetzky, B.
Systematic strain construction and process development: Xylitol production by Saccharomyces cerevisiae expressing Candida tenuis xylose reductase in wild-type or mutant form
Biores. Technol.
198
732-738
2015
Yamadazyma tenuis (O74237)
Xia, X.L.; Cong, S.; Weng, X.R.; Chen, J.H.; Wang, J.F.; Chou, K.C.
Molecular simulation to investigate the cofactor specificity for Pichia stipitis xylose reductase
Med. Chem.
9
985-992
2013
Scheffersomyces stipitis
Vogl, M.; Brecker, L.
Substrate binding to Candida tenuis xylose reductase during catalysis
RSC Adv.
3
25997-26004
2013
Yamadazyma tenuis
-
Cui, Z.; Mao, Y.; Zhao, Y.; Chen, C.; Tang, Y.; Chen, T.; Ma, H.; Wang, Z.
Concomitant cell-free biosynthesis of optically pure D-(-)-acetoin and xylitol via a novel NAD+ regeneration in two-enzyme cascade
J. Chem. Technol. Biotechnol.
93
3444-3451
2018
Yamadazyma tenuis (O74237)
-
Guo, J.; Huang, S.; Chen, Y.; Guo, X.; Xiao, D.
Heterologous expression of Spathaspora passalidarum xylose reductase and xylitol dehydrogenase genes improved xylose fermentation ability of Aureobasidium pullulans
Microb. Cell Fact.
17
64
2018
Spathaspora passalidarum (A0A0S2PJI4), Spathaspora passalidarum (S4WCW2), Spathaspora passalidarum
Nidetzky, B.; Brueggler, K.; Kratzer, R.; Mayr, P.
Multiple forms of xylose reductase in Candida intermedia comparison of their functional properties using quantitative structure-activity relationships, steady-state kinetic analysis, and pH studies
J. Agric. Food Chem.
51
7930-7935
2003
[Candida] intermedia
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