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1.1.1.413: A-factor type gamma-butyrolactone 1'-reductase (1S-forming)

This is an abbreviated version!
For detailed information about A-factor type gamma-butyrolactone 1'-reductase (1S-forming), go to the full flat file.

Reaction

a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one
+
NADP+
=
a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one
+
NADPH
+
H+

Synonyms

BARS1, Virginiae butanolide-specific dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.413 A-factor type gamma-butyrolactone 1'-reductase (1S-forming)

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.413 - A-factor type gamma-butyrolactone 1'-reductase (1S-forming)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
6-dehydro-Virginiae butanolide-A + NADPH + H+
(2R,3R,6S)-Virginiae butanolide-A + NADP+
show the reaction diagram