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Information on EC 1.1.1.413 - A-factor type gamma-butyrolactone 1'-reductase (1S-forming)

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IUBMB Comments
The enzyme, which is found in bacteria that produce virginiae-butanolide (VB) type gamma-butyrolactone autoregulators, reduces its substrate stereospecifically, forming a hydroxyl group in the (S) configuration.
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The enzyme appears in viruses and cellular organisms
Synonyms
BARS1, Virginiae butanolide-specific dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP+ = a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH + H+
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PATHWAY SOURCE
PATHWAYS
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