Reference on EC 1.4.3.21 - primary-amine oxidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yamada, H.; Yasunobu, K.T.
Monoamine oxidase II. Copper, one of the prosthetic groups of plasma monamine oxidase
J. Biol. Chem.
237
3077-3082
1962
Bos taurus
Carper, W.R.; Stoddard, D.D.; Martin, D.F.
Pig liver monoamine oxidase I: isolation and characterization
Biochim. Biophys. Acta
334
287-296
1974
Sus scrofa
-
Falk, M.C.; Staton, A.J.; Williams, T.J.
Heterogeneity of pig plasma amine oxidase: molecular and catalytic properties of chromatographically isolated forms
Biochemistry
22
3746-3751
1983
Sus scrofa
Lindstrm, A.; Olsson, B.; Petterson, G.
Effect of azide on some spectral and kinetic properties of pig-plasma benzylamine oxidase
Eur. J. Biochem.
48
237-243
1974
Sus scrofa
Lindstrm, A.; Olsson, B.; Petterson, G.
Kinetics of the interaction between pig-plasma benzylamine oxidase and hydrazine derivatives
Eur. J. Biochem.
42
177-182
1974
Sus scrofa
Barker, R.; Boden, N.; Cayley, G.; Charlton, S.C.; Henson, R.; Holmes, M.C.; Kelly, I.D.; Knowles, P.F.
Properties of cupric ions in benzylamine oxidase from pig plasma as studied by magnetic-resonance and kinetic methods
Biochem. J.
177
289-302
1979
Sus scrofa
Hysmith, R.M.; Boor, P.J.
Purification of benzylamine oxidase from cultured porcine aortic smooth muscle cells
Biochem. Cell Biol.
66
821-829
1988
Sus scrofa
Cai, D.; Klinman, J.P.
Copper amine oxidase: heterologous expression, purification, and characterization of an active enzyme in Saccharomyces cerevisiae
Biochemistry
33
7647-7653
1994
Ogataea angusta, Ogataea angusta 1A2V
Li, R.; Klinman, J.P.; Mathews, F.S.
Copper amine oxidase from Hansenula polymorpha: the crystal structure determined at 2.4 A resolution reveals the active conformation
Structure
6
293-307
1998
Ogataea angusta, Ogataea angusta 1A2V
Mills, S.A.; Klinman, J.P.
Evidence against reduction of Cu2+ to Cu+ during dioxygen activation in a copper amine oxidase from Yeast
J. Am. Chem. Soc.
122
9897-9904
2000
Ogataea angusta, Ogataea angusta 1A2V
-
Saysell, C.G.; Tambyrajah, W.S.; Murray, J.M.; Phillips, S.V.; McPherson, M.J.; Knowles, P.F.
Probing the catalytic mechanism of Escherichia coli amine oxidase using mutational variants and a reversible inhibitor as a substrate analogue
Biochem. J.
365
809-816
2002
Escherichia coli
Mills, S.A.; Goto, Y.; Su, Q.; Plastino, J.; Klinman, J.P.
Mechanistic comparison of the cobalt-substituted and wild-type copper amine oxidase from Hansenula polymorpha
Biochemistry
41
10577-10584
2002
Ogataea angusta
Lee, Y.; Ling, K.Q.; Lu, X.; Silverman, R.B.; Shepard, E.M.; Dooley, D.M.; Sayre, L.M.
3-Pyrrolines are mechanism-based inactivators of the quinone-dependent amine oxidases but only substrates of the flavin-dependent amine oxidases
J. Am. Chem. Soc.
124
12135-12143
2002
Bos taurus
Kishishita, S.; Okajima, T.; Kim, M.; Yamaguchi, H.; Hirota, S.; Suzuki, S.; Kuroda, S.; Tanizawa, K.; Mure, M.
Role of copper ion in bacterial copper amine oxidase: spectroscopic and crystallographic studies of metal-substituted enzymes
J. Am. Chem. Soc.
125
1041-1055
2003
Arthrobacter globiformis (P46881), Arthrobacter globiformis
Murakawa, T.; Okajima, T.; Kuroda, S.; Nakamoto, T.; Taki, M.; Yamamoto, Y.; Hayashi, H.; Tanizawa, K.
Quantum mechanical hydrogen tunneling in bacterial copper amine oxidase reaction
Biochem. Biophys. Res. Commun.
342
414-423
2006
Arthrobacter globiformis (P46881)
Okajima, T.; Kishishita, S.; Chiu, Y.C.; Murakawa, T.; Kim, M.; Yamaguchi, H.; Hirota, S.; Kuroda, S.; Tanizawa, K.
Reinvestigation of metal ion specificity for quinone cofactor biogenesis in bacterial copper amine oxidase
Biochemistry
44
12041-12048
2005
Arthrobacter globiformis (P46881), Arthrobacter globiformis
DuBois, J.L.; Klinman, J.P.
Role of a strictly conserved active site tyrosine in cofactor genesis in the copper amine oxidase from Hansenula polymorpha
Biochemistry
45
3178-3188
2006
Ogataea angusta
Chiu, Y.C.; Okajima, T.; Murakawa, T.; Uchida, M.; Taki, M.; Hirota, S.; Kim, M.; Yamaguchi, H.; Kawano, Y.; Kamiya, N.; Kuroda, S.; Hayashi, H.; Yamamoto, Y.; Tanizawa, K.
Kinetic and structural studies on the catalytic role of the aspartic acid residue conserved in copper amine oxidase
Biochemistry
45
4105-4120
2006
Arthrobacter globiformis (P46881), Arthrobacter globiformis
Takahashi, K.; Klinman, J.P.
Relationship of stopped flow to steady state parameters in the dimeric copper amine oxidase from Hansenula polymorpha and the role of zinc in inhibiting activity at alternate copper-containing subunits
Biochemistry
45
4683-4694
2006
Ogataea angusta
Ochiai, Y.; Itoh, K.; Sakurai, E.; Adachi, M.; Tanaka, Y.
Substrate selectivity of monoamine oxidase A, monoamine oxidase B, diamine oxidase, and semicarbazide-sensitive amine oxidase in COS-1 expression systems
Biol. Pharm. Bull.
29
2362-2366
2006
Rattus norvegicus (O08590)
Bertini, V.; Buffoni, F.; Ignesti, G.; Picci, N.; Trombino, S.; Iemma, F.; Alfei, S.; Pocci, M.; Lucchesini, F.; De Munno, A.
Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases
J. Med. Chem.
48
664-670
2005
Sus scrofa, Ogataea angusta (P12807), Ogataea angusta, Pisum sativum (Q42432), Pisum sativum
Longu, S.; Mura, A.; Padiglia, A.; Medda, R.; Floris, G.
Mechanism-based inactivators of plant copper/quinone containing amine oxidases
Phytochemistry
66
1751-1758
2005
Lens culinaris, Onobrychis viciifolia, Pisum sativum (Q43077), Lathyrus sativus (Q6A174)
Dai, X.; Ou, X.; Hao, X.; Cao, D.; Tang, Y.; Hu, Y.; Li, X.; Tang, C.
Synthetic liver X receptor agonist T0901317 inhibits semicarbazide-sensitive amine oxidase gene expression and activity in apolipoprotein E knockout mice
Acta Biochim. Biophys. Sin. (Shanghai)
40
261-268
2008
Mus musculus
Gokturk, C.; Sugimoto, H.; Blomgren, B.; Roomans, G.M.; Forsberg-Nilsson, K.; Oreland, L.; Sjoquist, M.
Macrovascular changes in mice overexpressing human semicarbazide-sensitive amine oxidase in smooth muscle cells
Am. J. Hypertens.
20
743-750
2007
Homo sapiens
Di Paolo, M.L.; Pesce, C.; Lunelli, M.; Scarpa, M.; Rigo, A.
N-alkanamines as substrates to probe the hydrophobic region of bovine serum amine oxidase active site: a kinetic and spectroscopic study
Arch. Biochem. Biophys.
465
50-60
2007
Bos taurus
Wang, G.J.; Lin, S.Y.; Wu, W.C.; Hou, W.C.
DPPH radical scavenging and semicarbazide-sensitive amine oxidase inhibitory and cytotoxic activities of Taiwanofungus camphoratus (Chang-chih)
Biosci. Biotechnol. Biochem.
71
1873-1878
2007
Homo sapiens, Mus musculus
Yraola, F.; Garcia-Vicente, S.; Marti, L.; Albericio, F.; Zorzano, A.; Royo, M.
Understanding the mechanism of action of the novel SSAO substrate (C7NH10)6(V10O28).2H2O, a prodrug of peroxovanadate insulin mimetics
Chem. Biol. Drug Des.
69
423-428
2007
Homo sapiens, Mus musculus, Rattus norvegicus
Dunkel, P.; Gelain, A.; Barlocco, D.; Haider, N.; Gyires, K.; Sperlagh, B.; Magyar, K.; Maccioni, E.; Fadda, A.; Matyus, P.
Semicarbazide-sensitive amine oxidase/vascular adhesion protein 1: recent developments concerning substrates and inhibitors of a promising therapeutic target
Curr. Med. Chem.
15
1827-1839
2008
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
Roessner, V.; Weber, A.; Becker, A.; Beck, G.; Frieling, H.; Bleich, S.
Decreased serum activity of semicarbazide-sensitive amine oxidase (SSAO) in patients treated with second generation antipsychotics: a link to impaired glucose metabolism ?
Eur. J. Clin. Pharmacol.
63
425-429
2007
Homo sapiens
Lin, S.Y.; Wang, C.C.; Lu, Y.L.; Wu, W.C.; Hou, W.C.
Antioxidant, anti-semicarbazide-sensitive amine oxidase, and anti-hypertensive activities of geraniin isolated from Phyllanthus urinaria
Food Chem. Toxicol.
46
2485-2492
2008
Bos taurus
Fracassini, L.; Alfarano, C.; Romagnani, B.; Pirisino, R.; Raimondi, L.
Endogenous substrates of the semicarbazide-sensitive amine oxidase increased nitric oxide production in rat white adipocytes
Inflamm. Res.
57
S53-S54
2008
Rattus norvegicus
Moore, R.H.; Spies, M.A.; Culpepper, M.B.; Murakawa, T.; Hirota, S.; Okajima, T.; Tanizawa, K.; Mure, M.
Trapping of a dopaquinone intermediate in the TPQ cofactor biogenesis in a copper-containing amine oxidase from Arthrobacter globiformis
J. Am. Chem. Soc.
129
11524-11534
2007
Arthrobacter globiformis (P46881), Arthrobacter globiformis
Langley, D.B.; Brown, D.E.; Cheruzel, L.E.; Contakes, S.M.; Duff, A.P.; Hilmer, K.M.; Dooley, D.M.; Gray, H.B.; Guss, J.M.; Freeman, H.C.
Enantiomer-specific binding of ruthenium(II) molecular wires by the amine oxidase of Arthrobacter globiformis
J. Am. Chem. Soc.
130
8069-8078
2008
Arthrobacter globiformis (P46881), Arthrobacter globiformis
Hernandez-Guillamon, M.; Bolea, I.; Sole, M.; Boada, M.; Tipton, K.F.; Unzeta, M.
Sodium bicarbonate enhances membrane-bound and soluble human semicarbazide-sensitive amine oxidase activity in vitro
J. Biochem.
142
571-576
2007
Homo sapiens
Lee, H.I.; Kim, Y.M.; Ro, Y.T.
Purification and characterization of a copper-containing amine oxidase from Mycobacterium sp. strain JC1 DSM 3803 grown on benzylamine
J. Biochem.
144
107-114
2008
Mycobacterium sp., Mycobacterium sp. DSM 3803 / JC1
Wiwanitkit, V.
Synergistic interaction between semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in diabetes: functional analysis by gene ontology
J. Diabetes Complicat.
22
413-419
2008
Homo sapiens (Q16853)
An, Z.; Jing, W.; Liu, Y.; Zhang, W.
Hydrogen peroxide generated by copper amine oxidase is involved in abscisic acid-induced stomatal closure in Vicia faba
J. Exp. Bot.
59
815-825
2008
Vicia faba
Leonetti, F.; Capaldi, C.; Pisani, L.; Nicolotti, O.; Muncipinto, G.; Stefanachi, A.; Cellamare, S.; Caccia, C.; Carotti, A.
Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase
J. Med. Chem.
50
4909-4916
2007
Homo sapiens
Olivieri, A.; Tipton, K.; O'Sullivan, J.
L-lysine as a recognition molecule for the VAP-1 function of SSAO
J. Neural Transm.
114
747-749
2007
Bos taurus
O'Sullivan, J.; Davey, G.; OSullivan, M.; Tipton, K.F.
Hydrogen peroxide derived from amine oxidation mediates the interaction between aminosugars and semicarbazide-sensitive amine oxidase
J. Neural Transm.
114
751-756
2007
Bos taurus
Yabanoglu, S.; Ucar, G.; Gokhan, N.; Salgin, U.; Yesilada, A.; Bilgin, A.A.
Interaction of rat lung SSAO with the novel 1-N-substituted thiocarbamoyl-3-substituted phenyl-5-(2-pyrolyl)-2-pyrazoline derivatives
J. Neural Transm.
114
769-773
2007
Rattus norvegicus
Bour, S.; Prevot, D.; Guigne, C.; Stolen, C.; Jalkanen, S.; Valet, P.; Carpene, C.
Semicarbazide-sensitive amine oxidase substrates fail to induce insulin-like effects in fat cells from AOC3 knockout mice
J. Neural Transm.
114
829-833
2007
Mus musculus
Nemcsik, J.; Szoekoe, E.; Soltesz, Z.; Fodor, E.; Toth, L.; Egresits, J.; Tabi, T.; Magyar, K.; Kiss, I.
Alteration of serum semicarbazide-sensitive amine oxidase activity in chronic renal failure
J. Neural Transm.
114
841-843
2007
Homo sapiens
Soltesz, Z.; Tabi, T.; Halasz, A.S.; Palfi, M.; Kocsis, E.; Magyar, K.; Toth, M.; Szoekoe, E.
Studies on the insulinomimetic effects of benzylamine, exogenous substrate of semicarbazide-sensitive amine oxidase enzyme in streptozotocin induced diabetic rats
J. Neural Transm.
114
851-855
2007
Rattus norvegicus
Unzeta, M.; Sole, M.; Boada, M.; Hernandez, M.
Semicarbazide-sensitive amine oxidase (SSAO) and its possible contribution to vascular damage in Alzheimers disease
J. Neural Transm.
114
857-862
2007
Homo sapiens
Vidrio, H.; Medina, M.
Hypotensive effect of hydroxylamine, an endogenous nitric oxide donor and SSAO inhibitor
J. Neural Transm.
114
863-865
2007
Rattus norvegicus
Sibon, I.; Mercier, N.; Darret, D.; Lacolley, P.; Lamaziere, J.M.
Association between semicarbazide-sensitive amine oxidase, a regulator of the glucose transporter, and elastic lamellae thinning during experimental cerebral aneurysm development: laboratory investigation
J. Neurosurg.
108
558-566
2008
Rattus norvegicus
ORourke, A.M.; Wang, E.Y.; Miller, A.; Podar, E.M.; Scheyhing, K.; Huang, L.; Kessler, C.; Gao, H.; Ton-Nu, H.T.; Macdonald, M.T.; Jones, D.S.; Linnik, M.D.
Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity
J. Pharmacol. Exp. Ther.
324
867-875
2008
Homo sapiens, Mus musculus, Rattus norvegicus
Takahashi, K.; Kakuta, I.; Sugimoto, H.; Obata, T.; Oreland, L.; Kinemuchi, H.
Absence of tissue-bound semicarbazide-sensitive amine oxidase activity in carp tissues
Life Sci.
80
1094-1099
2007
no activity in Cyprinus carpio
Jiang, Z.J.; Richardson, J.S.; Yu, P.H.
The contribution of cerebral vascular semicarbazide-sensitive amine oxidase to cerebral amyloid angiopathy in Alzheimers disease
Neuropathol. Appl. Neurobiol.
34
194-204
2008
Homo sapiens
Carpene, C.; Iffiu-Soltesz, Z.; Bour, S.; Prevot, D.; Valet, P.
Reduction of fat deposition by combined inhibition of monoamine oxidases and semicarbazide-sensitive amine oxidases in obese Zucker rats
Pharmacol. Res.
56
522-530
2007
Rattus norvegicus
Prevot, D.; Soltesz, Z.; Abello, V.; Wanecq, E.; Valet, P.; Unzeta, M.; Carpene, C.
Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats
Pharmacol. Res.
56
70-79
2007
Rattus norvegicus
Carpene, C.; Abello, V.; Iffiu-Soltesz, Z.; Mercier, N.; Feve, B.; Valet, P.
Limitation of adipose tissue enlargement in rats chronically treated with semicarbazide-sensitive amine oxidase and monoamine oxidase inhibitors
Pharmacol. Res.
57
426-434
2008
Rattus norvegicus
Pirrat, P.; Smith, M.A.; Pearson, A.R.; McPherson, M.J.; Phillips, S.E.
Structure of a xenon derivative of Escherichia coli copper amine oxidase: confirmation of the proposed oxygen-entry pathway
Acta Crystallogr. Sect. F
64
1105-1109
2008
Escherichia coli (P46883), Escherichia coli
Atkin, K.E.; Reiss, R.; Turner, N.J.; Brzozowski, A.M.; Grogan, G.
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of variants of monoamine oxidase from Aspergillus niger
Acta Crystallogr. Sect. F
64
182-185
2008
Aspergillus niger
Langley, D.B.; Trambaiolo, D.M.; Duff, A.P.; Dooley, D.M.; Freeman, H.C.; Guss, J.M.
Complexes of the copper-containing amine oxidase from Arthrobacter globiformis with the inhibitors benzylhydrazine and tranylcypromine
Acta Crystallogr. Sect. F
64
577-583
2008
Arthrobacter globiformis (P46881), Arthrobacter globiformis
Nunes, S.F.; Figueiredo, I.V.; Soares, P.J.; Costa, N.E.; Lopes, M.C.; Caramona, M.M.
Semicarbazide-sensitive amine oxidase activity and total nitrite and nitrate concentrations in serum: novel biochemical markers for type 2 diabetes?
Acta Diabetol.
46
135-140
2009
Homo sapiens
Bour, S.; Caspar-Bauguil, S.; Iffiu-Soltesz, Z.; Nibbelink, M.; Cousin, B.; Miiluniemi, M.; Salmi, M.; Stolen, C.; Jalkanen, S.; Casteilla, L.; Penicaud, L.; Valet, P.; Carpene, C.
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition
Am. J. Pathol.
174
1075-1083
2009
Mus musculus
Kaitaniemi, S.; Elovaara, H.; Groen, K.; Kidron, H.; Liukkonen, J.; Salminen, T.; Salmi, M.; Jalkanen, S.; Elima, K.
The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase
Cell. Mol. Life Sci.
66
2743-2757
2009
Homo sapiens (O75106), Homo sapiens (Q16853)
Peter, C.; Laliberte, J.; Beaudoin, J.; Labbe, S.
Copper distributed by Atx1 is available to copper amine oxidase 1 in Schizosaccharomyces pombe
Eukaryot. Cell
7
1781-1794
2008
no activity in Saccharomyces cerevisiae, Schizosaccharomyces pombe, Schizosaccharomyces pombe FY435 / ATCC 87284
Atkin, K.E.; Reiss, R.; Koehler, V.; Bailey, K.R.; Hart, S.; Turkenburg, J.P.; Turner, N.J.; Brzozowski, A.M.; Grogan, G.
The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution
J. Mol. Biol.
384
1218-1231
2008
Aspergillus niger
Iffiu-Soltesz, Z.; Prevot, D.; Carpene, C.
Influence of prolonged fasting on monoamine oxidase and semicarbazide-sensitive amine oxidase activities in rat white adipose tissue
J. Physiol. Biochem.
65
11-23
2009
Rattus norvegicus
Vavilova, T.; Ostrovskaya, I.; Axenova, L.; Buneeva, O.; Medvedev, A.
Monoamine oxidase and semicarbazide sensitive amine oxidase activities in normal and inflamed human dental pulp
Med. Sci. Monit.
15
BR289-BR292
2009
Homo sapiens
Stevanato, R.; Cardillo, S.; Braga, M.; De Iuliis, A.; Battaglia, V.; Toninello, A.; Agostinelli, E.; Vianello, F.
Preliminary kinetic characterization of a copper amine oxidase from rat liver mitochondria matrix
Amino Acids
40
713-720
2011
Rattus norvegicus
Liang, G.; Choi-Sledeski, Y.M.; Poli, G.; Chen, X.; Shum, P.; Minnich, A.; Wang, Q.; Tsay, J.; Sides, K.; Cairns, J.; Stoklosa, G.; Nieduzak, T.; Zhao, Z.; Wang, J.; Vaz, R.J.
A conformationally constrained inhibitor with an enhanced potency for beta-tryptase and stability against semicarbazide-sensitive amine oxidase (SSAO)
Bioorg. Med. Chem. Lett.
20
6721-6724
2010
Homo sapiens
Haider, N.; Hochholdinger, I.; Matyus, P.; Wobus, A.
Synthesis of ortho-functionalized 4-aminomethylpyridazines as substrate-like semicarbazide-sensitive amine oxidase inhibitors
Chem. Pharm. Bull.
58
964-970
2010
Homo sapiens
Martelius, T.; Salmi, M.; Krogerus, L.; Loginov, R.; Schoultz, M.; Karikoski, M.; Miiluniemi, M.; Soots, A.; Hoeckerstedt, K.; Jalkanen, S.; Lautenschlager, I.
Inhibition of semicarbazide-sensitive amine oxidases decreases lymphocyte infiltration in the early phases of rat liver allograft rejection
Int. J. Immunopathol. Pharmacol.
21
911-920
2009
Rattus norvegicus
Nurminen, E.M.; Pihlavisto, M.; Lazar, L.; Szakonyi, Z.; Pentikaeinen, U.; Fueloep, F.; Pentikaeinen, O.T.
Synthesis, in vitro activity, and three-dimensional quantitative structure-activity relationship of novel hydrazine inhibitors of human vascular adhesion protein-1
J. Med. Chem.
53
6301-6315
2010
Homo sapiens (Q16853), Homo sapiens
Jeon, H.B.; Jang, Y.
Reversible inactivation of bovine plasma amine oxidase by cysteamine and related analogs
Biochem. Biophys. Res. Commun.
403
442-446
2010
Bos taurus
Smith, M.A.; Pirrat, P.; Pearson, A.R.; Kurtis, C.R.; Trinh, C.H.; Gaule, T.G.; Knowles, P.F.; Phillips, S.E.; McPherson, M.J.
Exploring the roles of the metal ions in Escherichia coli copper amine oxidase
Biochemistry
49
1268-1280
2010
Escherichia coli (P46883), Escherichia coli
Chang, C.M.; Klema, V.J.; Johnson, B.J.; Mure, M.; Klinman, J.P.; Wilmot, C.M.
Kinetic and structural analysis of substrate specificity in two copper amine oxidases from Hansenula polymorpha
Biochemistry
49
2540-2550
2010
Ogataea angusta (P12807), Ogataea angusta
Elovaara, H.; Kidron, H.; Parkash, V.; Nymalm, Y.; Bligt, E.; Ollikka, P.; Smith, D.; Pihlavisto, M.; Salmi, M.; Jalkanen, S.; Salminen, T.
Identification of two imidazole binding sites and key residues for substrate specificity in human primary amine oxidase AOC3
Biochemistry
50
5507-5520
2011
Homo sapiens (Q16853), Homo sapiens
McGrath, A.P.; Mithieux, S.M.; Collyer, C.A.; Bakhuis, J.G.; van den Berg, M.; Sein, A.; Heinz, A.; Schmelzer, C.; Weiss, A.S.; Guss, J.M.
Structure and activity of Aspergillus nidulans copper amine oxidase
Biochemistry
50
5718-5730
2011
Aspergillus nidulans
Klema, V.J.; Solheid, C.J.; Klinman, J.P.; Wilmot, C.M.
Structural analysis of aliphatic versus aromatic substrate specificity in a copper amine oxidase from Hansenula polymorpha
Biochemistry
52
2291-2301
2013
Ogataea angusta (P12807), Ogataea angusta
Foot, J.S.; Deodhar, M.; Turner, C.I.; Yin, P.; van Dam, E.M.; Silva, D.G.; Olivieri, A.; Holt, A.; McDonald, I.A.
The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1)
Bioorg. Med. Chem. Lett.
22
3935-3940
2012
Homo sapiens
Sun, J.; Morita, H.; Chen, G.; Noguchi, H.; Abe, I.
Molecular cloning and characterization of copper amine oxidase from Huperzia serrata
Bioorg. Med. Chem. Lett.
22
5784-5790
2012
Huperzia serrata (I6NC69), Huperzia serrata
Planas-Portell, J.; Gallart, M.; Tiburcio, A.; Altabella, T.
Copper-containing amine oxidases contribute to terminal polyamine oxidation in peroxisomes and apoplast of Arabidopsis thaliana
BMC Plant Biol.
13
109
2013
Arabidopsis thaliana (F4IAX1), Arabidopsis thaliana (Q8H1H9), Arabidopsis thaliana (Q8L866)
Murakawa, T.; Hayashi, H.; Taki, M.; Yamamoto, Y.; Kawano, Y.; Tanizawa, K.; Okajima, T.
Structural insights into the substrate specificity of bacterial copper amine oxidase obtained by using irreversible inhibitors
J. Biochem.
151
167-178
2012
Arthrobacter globiformis
Johnson, B.J.; Yukl, E.T.; Klema, V.J.; Klinman, J.P.; Wilmot, C.M.
Structural snapshots from the oxidative half-reaction of a copper amine oxidase: implications for O2 activation
J. Biol. Chem.
288
28409-28417
2013
Ogataea angusta (P12807)
Mills, S.A.; Brown, D.E.; Dang, K.; Sommer, D.; Bitsimis, A.; Nguyen, J.; Dooley, D.M.
Cobalt substitution supports an inner-sphere electron transfer mechanism for oxygen reduction in pea seedling amine oxidase
J. Biol. Inorg. Chem.
17
507-515
2012
Pisum sativum
Foster, A.; Barnes, N.; Speight, R.; Keane, M.
Identification, functional expression and kinetic analysis of two primary amine oxidases from Rhodococcus opacus
J. Mol. Catal. B
74
73-82
2012
Rhodococcus opacus, Rhodococcus opacus DSM 43250
-
Shen, S.H.; Wertz, D.L.; Klinman, J.P.
Implication for functions of the ectopic adipocyte copper amine oxidase (AOC3) from purified enzyme and cell-based kinetic studies
PLoS ONE
7
e29270
2012
Homo sapiens (Q16853), Homo sapiens
Pintus, F.; Spano, D.; Floris, G.; Medda, R.
Euphorbia characias latex amine oxidase and peroxidase: interacting enzymes?
Protein J.
32
435-441
2013
Euphorbia characias (Q9SW90), Euphorbia characias
Lee, J.I.; Kim, Y.W.
Characterization of amine oxidases from Arthrobacter aurescens and application for determination of biogenic amines
World J. Microbiol. Biotechnol.
29
673-682
2013
Paenarthrobacter aurescens (A1R2C3), Paenarthrobacter aurescens (A1RDD3), Paenarthrobacter aurescens, Paenarthrobacter aurescens TC1 (A1R2C3), Paenarthrobacter aurescens TC1 (A1RDD3)
Dainese, E.; Sabatucci, A.; Pintus, F.; Medda, R.; Angelucci, C.B.; Floris, G.; Maccarrone, M.
Domain mobility as probed by small-angle X-ray scattering may account for substrate access to the active site of two copper-dependent amine oxidases
Acta Crystallogr. Sect. D
70
2101-2110
2014
Lens culinaris (P49252), Euphorbia characias (Q9SW90)
Lucchesini, F.; Pocci, M.; Alfei, S.; Bertini, V.; Buffoni, F.
Synthesis of 2,6-disubstituted benzylamine derivatives as reversible selective inhibitors of copper amine oxidases
Bioorg. Med. Chem.
22
1558-1567
2014
Sus scrofa
Tavladoraki, P.; Cona, A.; Angelini, R.
Copper-containing amine oxidases and FAD-dependent polyamine oxidases are key players in plant tissue differentiation and organ development
Front. Plant Sci.
7
824
2016
Arabidopsis thaliana
Huang, A.; Wang, Y.; She, X.; Mu, J.; Zhao, J.
Copper amine oxidase-catalysed hydrogen peroxide involves production of nitric oxide in darkness-induced stomatal closure in broad bean
Funct. Plant Biol.
42
1057-1067
2015
Vicia faba
-
Murakawa, T.; Hamaguchi, A.; Nakanishi, S.; Kataoka, M.; Nakai, T.; Kawano, Y.; Yamaguchi, H.; Hayashi, H.; Tanizawa, K.; Okajima, T.
probing the catalytic mechanism of copper amine oxidase from Arthrobacter globiformis with halide ions
J. Biol. Chem.
290
23094-23109
2015
Arthrobacter globiformis (P46881), Arthrobacter globiformis
Sugawara, A.; Matsui, D.; Yamada, M.; Asano, Y.; Isobe, K.
Characterization of two amine oxidases from Aspergillus carbonarius AIU 205
J. Biosci. Bioeng.
119
629-635
2015
Aspergillus carbonarius, Aspergillus carbonarius AIU 205
Gross, F.; Rudolf, E.E.; Thiele, B.; Durner, J.; Astier, J.
Copper amine oxidase 8 regulates arginine-dependent nitric oxide production in Arabidopsis thaliana
J. Exp. Bot.
68
2149-2162
2017
Arabidopsis thaliana (F4IAX0), Arabidopsis thaliana
Zhang, Y.; Li, G.; Zhong, R.; Ma, Y.; Gong, P.; Zhang, F.
Characterization of the copper-containing amine oxidase from Trifolium pratense seedlings
Nucl. Sci. Tech.
27
69
2016
Trifolium pratense
-
Zarei, A.; Trobacher, C.P.; Cooke, A.R.; Meyers, A.J.; Hall, J.C.; Shelp, B.J.
Apple fruit copper amine oxidase isoforms peroxisomal MdAO1 prefers diamines as substrates, whereas extracellular MdAO2 exclusively utilizes monoamines
Plant Cell Physiol.
56
137-147
2015
Malus domestica
Cona, A.; Tisi, A.; Ghuge, S.A.; Franchi, S.; De Lorenzo, G.; Angelini, R.
Wound healing response and xylem differentiation in tobacco plants over-expressing a fungal endopolygalacturonase is mediated by copper amine oxidase activity
Plant Physiol. Biochem.
82
54-65
2014
Nicotiana tabacum
Elovaara, H.; Huusko, T.; Maksimow, M.; Elima, K.; Yegutkin, G.G.; Skurnik, M.; Dobrindt, U.; Siitonen, A.; McPherson, M.J.; Salmi, M.; Jalkanen, S.
Primary amine oxidase of Escherichia coli is a metabolic enzyme that can use a human leukocyte molecule as a substrate
PLoS ONE
10
e0142367
2015
Escherichia coli
Song, X.; She, X.; Yue, M.; Liu, Y.; Wang, Y.; Zhu, X.; Huang, A.
Involvement of copper amine oxidase (CuAO)-dependent hydrogen peroxide synthesis in ethylene-induced stomatal closure in Vicia faba
Russ. J. Plant Physiol.
61
390-396
2014
Vicia faba
-
Murakawa, T.; Baba, S.; Kawano, Y.; Hayashi, H.; Yano, T.; Kumasaka, T.; Yamamoto, M.; Tanizawa, K.; Okajima, T.
In crystallo thermodynamic analysis of conformational change of the topaquinone cofactor in bacterial copper amine oxidase
Proc. Natl. Acad. Sci. USA
116
135-140
2019
Arthrobacter globiformis (P46881), Arthrobacter globiformis
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