2.3.1.194: acetoacetyl-CoA synthase

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For detailed information about acetoacetyl-CoA synthase, go to the full flat file.

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Synonyms

AACS, Acetoacetyl-CoA synthase, Acetoacetyl-CoA synthetase, acetoacetyl-coenzyme A synthase, acetoacetyl-coenzyme A synthesizing enzyme, More, NphT7, nphT7SCL, thiolase superfamily acetoacetyl-CoA synthase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.194 acetoacetyl-CoA synthase

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Results	in table
41	AA Sequence
5	Application
7	Cloned(Commentary)
1	Expression
6	General Information
6	KM Value [mM]
4	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
9	Organism
1	pH Optimum
9	Protein Variants
1	Purification (Commentary)
2	Reaction
7	Reference
5	Source Tissue
2	Specific Activity [micromol/min/mg]
10	Substrates and Products (Substrate)
2	Subunits
21	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

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Cloned on EC 2.3.1.194 - acetoacetyl-CoA synthase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

AACS expression analysis during development, overview

Mus musculus

-

718764

co-expression of polyhydroxyalkanoate synthase, PhaC, from Ralstonia eutropha with acetoacetyl-CoA synthetase in Escherichia coli and Corynebacterium glutamicum leading to enhanced production of polyhydroxybutanoates, by cloning the AACS gene into the phaABC operon of Ralstonia eutropha. Overexpression of AACS leads to a great enhancement of the malonyl-CoA pool in Escherichia coli

Streptomyces sp.

-

714539

gene nphT7, functional recombinant expression in sugarcane (Saccharum sp.) cultivar Q117, coexpression of gene nphT7 with genes phaB and phaC

Streptomyces sp. CL190

D7URV0

746014

gene nphT7, organized in the mevalonate pathway gene cluster, functional expression in Streptomyces albus, overexpression of N-terminally His8-tagged enzyme in Escherichia coli

Streptomyces sp.

-

706551

gene nphT7, recombinant expression in Saccharomyces cerevisiae strain CEN, analysis of the effect of acetoacetyl-CoA synthase on growth as well as the production of farnesene and compares different homologues regarding their efficiency

Streptomyces sp. CL190

D7URV0

745496

overexpressed in Escherichia coli as an N-terminal His8-tagged protein

Streptomyces sp.

-

706551

recombinant expression of AACS in Corynebacterium glutamicum and Escherichia coli leads to aquired ability to form poly(3-hydroxybutyrate) in the transformed organisms by 19.7 wt% and 10.5 wt%, respectively, biosynthetic pathway, overview

Streptomyces sp.

-

714539