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2.3.1.194: acetoacetyl-CoA synthase

This is an abbreviated version!
For detailed information about acetoacetyl-CoA synthase, go to the full flat file.

Word Map on EC 2.3.1.194

Reaction

acetyl-CoA
+
malonyl-CoA
=
acetoacetyl-CoA
+
CoA
+
CO2

Synonyms

AACS, Acetoacetyl-CoA synthase, Acetoacetyl-CoA synthetase, acetoacetyl-coenzyme A synthase, acetoacetyl-coenzyme A synthesizing enzyme, More, NphT7, nphT7SCL, thiolase superfamily acetoacetyl-CoA synthase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.194 acetoacetyl-CoA synthase

Application

Application on EC 2.3.1.194 - acetoacetyl-CoA synthase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
biotechnology
medicine
histological changes, decreased steroid hormone concentrations and decreased cholesterol supply are observed in nicotine-treated fetal adrenals. The expression of genes regulating ketone metabolic process decreases in nicotine-treated fetal adrenals. Acetoacetyl-CoA synthetase (AACS), the enzyme utilizing ketones for cholesterol supply, displays decreased expression and increased DNA methylation in the proximal promoter of AACS
synthesis