1.14.14.142: 8-dimethylallylnaringenin 2'-hydroxylase

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For detailed information about 8-dimethylallylnaringenin 2'-hydroxylase, go to the full flat file.

Reaction

Synonyms

8-dimethylallylnaringenin 2'-hydroxylase, 8-DMAN 2'-hydroxylase, EC 1.14.13.103

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.142 8-dimethylallylnaringenin 2'-hydroxylase

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Results	in table
1	CAS Registry Number
2	Cofactor
6	Inhibitors
1	KM Value [mM]
3	Localization
2	Natural Substrates/ Products (Substrates)
2	Organism
1	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
2	Reference
2	Source Tissue
5	Substrates and Products (Substrate)
3	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 1.14.14.142 - 8-dimethylallylnaringenin 2'-hydroxylase

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sophoraflavanone-B,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (2'-hydroxylating)

A membrane-bound cytochrome P-450 (heme-thiolate) protein that is associated with the endoplasmic reticulum [1,2]. This enzyme is specific for sophoraflavanone B as substrate. Along with EC 2.5.1.70 (naringenin 8-dimethylallyltransferase) and EC 2.5.1.71 (leachianone G 2''-dimethylallyltransferase), this enzyme forms part of the sophoraflavanone G biosynthetic pathway.