1.14.14.142: 8-dimethylallylnaringenin 2'-hydroxylase

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For detailed information about 8-dimethylallylnaringenin 2'-hydroxylase, go to the full flat file.

8-dimethylallylnaringenin 2'-hydroxylase, 8-DMAN 2'-hydroxylase, EC 1.14.13.103

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Results	in table
1	CAS Registry Number
2	Cofactor
6	Inhibitors
1	KM Value [mM]
3	Localization
2	Natural Substrates/ Products (Substrates)
2	Organism
1	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
2	Reference
2	Source Tissue
5	Substrates and Products (Substrate)
3	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Substrates Products on EC 1.14.14.142 - 8-dimethylallylnaringenin 2'-hydroxylase

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(-)-(2S)-8-dimethylallylnaringenin + [oxidized NADPH-hemoprotein reductase] + H2O

leachianone G + [oxidized NADPH-hemoprotein reductase] + H2O

i.e. sophoraflavanone B, the enzyme catalyzes the 2'-hydroxylation of 8-DMAN and is O2-dependent

8-dimethylallylnaringenin + [reduced NADPH-hemoprotein reductase] + O2

leachianone G + [oxidized NADPH-hemoprotein reductase] + H2O

additional information

the enzyme is a cytochrome P450 monooxygenase