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1.14.14.117: aflatoxin B synthase

This is an abbreviated version!
For detailed information about aflatoxin B synthase, go to the full flat file.

Reaction

8-O-methyldihydrosterigmatocystin
+ 2 [reduced NADPH-hemoprotein reductase] + 2 O2 =
Aflatoxin B2
+ 2 [oxidized NADPH-hemoprotein reductase] +
H2O
+
methanol
+
CO2

Synonyms

aflQ, EC 1.14.13.175, ordA

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.117 aflatoxin B synthase

Natural Substrates Products

Natural Substrates Products on EC 1.14.14.117 - aflatoxin B synthase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
8-O-methyldihydrosterigmatocystin + [reduced NADPH-hemoprotein reductase] + O2
aflatoxin B2 + methanol + CO2 + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
8-O-methylsterigmatocystin + [reduced NADPH-hemoprotein reductase] + O2
aflatoxin B1 + 2 NADP+ + methanol + [oxidized NADPH-hemoprotein reductase] + H2O + CO2
show the reaction diagram