EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.3.1.108 | alpha-tubulin n-acetyltransferase deficiency |
18430410 |
Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells. |
causal interaction therapeutic application unassigned |
4 1 0 |
2.3.1.108 | alpha-tubulin n-acetyltransferase deficiency |
22972992 |
MEC-17 Deficiency Leads to Reduced ?-Tubulin Acetylation and Impaired Migration of Cortical Neurons. |
causal interaction unassigned |
3 0 |
2.3.1.108 | alpha-tubulin n-acetyltransferase deficiency |
32296180 |
Germline Elongator mutations in Sonic Hedgehog medulloblastoma. |
causal interaction unassigned |
1 0 |
2.3.1.108 | Amyotrophic Lateral Sclerosis |
20107598 |
The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation. |
unassigned |
0 |
2.3.1.108 | Amyotrophic Lateral Sclerosis |
27847465 |
The Many Faces of Elongator in Neurodevelopment and Disease. |
causal interaction unassigned |
3 0 |
2.3.1.108 | Amyotrophic Lateral Sclerosis |
28667575 |
Animal and cellular models of familial dysautonomia. |
unassigned |
0 |
2.3.1.108 | Ataxia Telangiectasia |
20159970 |
MYST family lysine acetyltransferase facilitates ataxia telangiectasia mutated (ATM) kinase-mediated DNA damage response in Toxoplasma gondii. |
unassigned |
0 |
2.3.1.108 | Breast Neoplasms |
33995658 |
KAT6A, a novel regulator of ?-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 4 3 |
2.3.1.108 | Breast Neoplasms |
34199510 |
Microtubule Acetylation Controls MDA-MB-231 Breast Cancer Cell Invasion through the Modulation of Endoplasmic Reticulum Stress. |
causal interaction diagnostic usage ongoing research unassigned |
3 4 2 0 |
2.3.1.108 | Carcinogenesis |
26638912 |
A bivalent role of TIP60 histone acetyl transferase in human cancer. |
causal interaction ongoing research therapeutic application unassigned |
4 4 4 0 |