EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.1.1.205 | Adenocarcinoma of Lung |
6475642 |
Novel nucleoside inhibitors of guanosine metabolism as antitumor agents. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 1.1.1.205 | Adenocarcinoma of Lung |
32021289 |
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway. |
unassigned |
0 |
| 1.1.1.205 | Agranulocytosis |
26237184 |
Genetic variants in 6-mercaptopurine pathway as potential factors of hematological toxicity in acute lymphoblastic leukemia patients. |
ongoing research
unassigned |
4
0 |
| 1.1.1.205 | Anemia |
28730859 |
Molecular targeting of inosine-5'-monophosphate dehydrogenase by FF-10501 promotes erythropoiesis via ROS/MAPK pathway. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 1.1.1.205 | Arthritis, Experimental |
17585753 |
Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419). |
ongoing research
therapeutic application
unassigned |
2
4
0 |
| 1.1.1.205 | Arthritis, Rheumatoid |
17002220 |
Inosine 5'-monophosphate dehydrogenase inhibitors for the treatment of autoimmune diseases. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 1.1.1.205 | Arthritis, Rheumatoid |
23283538 |
Safety and efficacy of mizoribine in patients with connective tissue diseases other than rheumatoid arthritis. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 1.1.1.205 | Arthritis, Rheumatoid |
28502927 |
Mizoribine Synchronized Methotrexate Therapy should be Considered when Treating Rheumatoid Arthritis Patients with an Inadequate Response to Various Combination Therapies. |
diagnostic usage
therapeutic application
unassigned |
3
4
0 |
| 1.1.1.205 | Autoimmune Diseases |
17002220 |
Inosine 5'-monophosphate dehydrogenase inhibitors for the treatment of autoimmune diseases. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 1.1.1.205 | Autoimmune Diseases |
17659481 |
Recent development of IMP dehydrogenase inhibitors for the treatment of cancer. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
