EC Number   |
Expression |
Reference |
|---|
    2.3.1.57 | down |
the SSAT activity in carbon tetrachloride-treated rats declined rapidly after treatment with cycloheximide |
701622 |
| 2.3.1.57 | more |
spermidine/spermine N1-acetyltransferase SSAT, has an alternative mRNA splice variant SSATX which undergoes degradation via nonsense-mediated mRNA decay (NMD) pathway, and the intracellular polyamine level regulates the ratio of the SSATX and SSAT splice variants |
718560 |
| 2.3.1.57 | up |
antitumorigenicity of upregulated SSAT |
703035 |
| 2.3.1.57 | up |
bltD gene expression is strongly increased by spermine but not agmatine, putrescine or spermidine addition |
-, 757344 |
| 2.3.1.57 | up |
both cold and beta3-adrenergic receptor agonist CL-316,243 increase the expression of the enzyme in inguinal white adipose tissue and brown adipose tissue |
757571 |
| 2.3.1.57 | up |
high levels of enzyme expression are measured in tumor human cell lines, and in breast, prostate and lung tumor tissue. Increases in enzyme protein contents and gene expression in primary tumors is linked to a concomitant higher level of N1-acetylamantadine in urine of cancer patients upon ingestion of amantadine |
756851 |
| 2.3.1.57 | up |
induction of enzyme SSAT with alpha-methylspermidine disturbs wild-type osteoblastogenesis |
-, 737285 |
| 2.3.1.57 | up |
induction of SSAT gene expression by combined quinoxalines and spermidine analogue treatment, overview. The cDDP-resistant human ovarian cell line, A2780/CP, shows defective expression and inducibility of SSAT by Spm analogues, when compared to the sensitive counterpart A2780 |
703928 |
| 2.3.1.57 | up |
lithium induces enzyme expression in low and high risk groups for suicide commitment as well as in controls, but it has no effect in suicide completers. Differences in lithium-induced increase in SAT1 mRNA levels, overview |
736271 |
| 2.3.1.57 | up |
N',N''-diethylnorspermine, N'-ethyl-N''-[(cyclopropyl)-methy]-4,8-diazaundecane, and N'-ethyl-N''-[(cycloheptyl)methy]-4,8-diazaundecane treatments lead to high, moderate, or low induction of SSAT activity, respectively |
702136 |
