EC Number |
Expression |
Reference |
---|
1.1.1.95 | down |
a sericin-deficient silkworm strain displays reduced expression of bmphgdh mRNA |
762680 |
1.1.1.95 | down |
HOXA10 is required for enzyme regulation in the endometrium, HOAX sense expression causes a 2.0fold downregulation of 3-PGDH in endometrial cells |
701170 |
1.1.1.95 | down |
mRNA transcriptional expression for BvPGDHb is significantly reduced under salt stress conditions |
763677 |
1.1.1.95 | down |
Phgdh knockout mouse embryos demonstrate that free serine and glycine concentrations are decreased markedly in head samples |
698067 |
1.1.1.95 | more |
there is no significant change in the mRNA expression level after the incubation with L-serine |
-, 739236 |
1.1.1.95 | up |
AtPGDH1 gene is coexpressed with genes of tryptophan biosynthesis. Activators of tryptophan biosynthesis MYB51 and MYB34 are involved in the expression of AtPGDH1 |
763716 |
1.1.1.95 | up |
HOXA10 is required for enzyme regulation in the endometrium, HOAX antisense expression, siRNA, causes a 4.4fold upregulation of 3-PGDH in endometrial cells |
701170 |
1.1.1.95 | up |
mRNA transcriptional expression for BvPGDHa is significantly enhanced under salt stress conditions in both leaves and roots |
763677 |
1.1.1.95 | up |
the enzyme is highly expressed in tumors as a result of amplification, transcription, or its degradation and stability alteration, which dysregulates the serine biosynthesis pathway via metabolic enzyme activity to nourish tumors. High expression of the enzyme is dramatically related to tumor resistance to chemotherapies |
763147 |