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Literature summary for 2.1.1.373 extracted from

  • Sun, H.; Zhang, Y.; Tan, S.; Zheng, Y.; Zhou, S.; Ma, Q.-Y.; Yang, G.-P.; Todd, J.D.; Zhang, X.-H.
    DMSP-producing bacteria are more abundant in the surface microlayer than subsurface seawater of the east china sea (2020), Microb. Ecol., 80, 350-365 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + (2R)-2-hydroxy-4-(methylsulfanyl)butanoate bacterium the enzyme is involved in biosynthesis of dimethylsulfoniopropionate S-adenosyl-L-homocysteine + (2R)-4-(dimethylsulfaniumyl)-2-hydroxybutanoate
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 ?

Organism

Organism UniProt Comment Textmining
bacterium
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 by interrogating the Ocean Microbial Reference Gene Catalogue Metagenomic Database (OM-RGC25; predominantly surface seawater samples), dsyB is predicted to be present in up to 0.35% of bacteria. Sea surface microlayer samples possesse about 3fold higher dsyB transcripts than those from subsurface seawater samples
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + (2R)-2-hydroxy-4-(methylsulfanyl)butanoate
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 bacterium S-adenosyl-L-homocysteine + (2R)-4-(dimethylsulfaniumyl)-2-hydroxybutanoate
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 ?
S-adenosyl-L-methionine + (2R)-2-hydroxy-4-(methylsulfanyl)butanoate the enzyme is involved in biosynthesis of dimethylsulfoniopropionate bacterium S-adenosyl-L-homocysteine + (2R)-4-(dimethylsulfaniumyl)-2-hydroxybutanoate
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 ?

Synonyms

Synonyms Comment Organism
dsyB
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 bacterium
methylthiohydroxybutyrate S-methyltransferase
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 bacterium
MTHB S-methyltransferase
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 bacterium

General Information

General Information Comment Organism
evolution the bacterial DsyB enzyme is homologous to the algal DSYB enzyme and likely originates in bacteria bacterium