Application | Comment | Organism |
---|---|---|
analysis | development of a mouse model with decreased coenzyme Q, CoQ, transgsgene expression of COQ7/CLK-1. The mice show a concomitant decrease in CoQ9, mitochondrial respiratory enzyme activity and the generation of reactive oxygen species in the mitochondria | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Mus musculus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P97478 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
clk-1 | - |
Mus musculus |
COQ7 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | promoter-driven COQ7/CLK-1 expression providing low levels of transgene expression rescues COQ7-deficient mice from embryonic lethality. The mice show a concomitant decrease in CoQ9, mitochondrial respiratory enzyme activity and the generation of reactive oxygen species in the mitochondria | Mus musculus |