2.3.1.B25: octaketide synthase
This is an abbreviated version!
For detailed information about octaketide synthase, go to the full flat file.
Word Map on EC 2.3.1.B25
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2.3.1.B25
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plant-specific
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aloe
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arborescens
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condensations
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pentaketide
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chromone
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anthraquinone
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dynemicins
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micromonospora
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10-membered
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benzophenone
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calicheamicin
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hexaketide
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precursor-directed
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anthrone
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naphthopyrone
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benzalacetone
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nonaketide
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n-methylanthraniloyl-coa
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acridone
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spring-8
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palmatum
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tetraketides
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neocarzinostatin
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synthesis
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molecular biology
- 2.3.1.B25
-
plant-specific
- aloe
- arborescens
-
condensations
-
pentaketide
- chromone
- anthraquinone
- dynemicins
- micromonospora
-
10-membered
- benzophenone
-
calicheamicin
-
hexaketide
-
precursor-directed
- anthrone
-
naphthopyrone
- benzalacetone
-
nonaketide
- n-methylanthraniloyl-coa
-
acridone
-
spring-8
- palmatum
-
tetraketides
-
neocarzinostatin
- synthesis
- molecular biology
Reaction
16 malonyl-CoA + 28 H+ = 16 CoA + + + 16 CO2 + 16 H2O
Synonyms
AaOKS, DynE8, enediyne PKS, enediyne polyketide synthase, OKS, oktaketide synthase, PksE, plant type III OKS, plant type III polyketide synthase
ECTree
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Application
Application on EC 2.3.1.B25 - octaketide synthase
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molecular biology
use of octaketide synthase for rational biosynthetic engineering to generate molecular diversity and pursue innovative, biologically potent compounds
synthesis
the enzyme can be used in the production of carminic acid, a C-glucosylated octaketide anthraquinone and the main constituent of the natural dye carmine (E120). Carmine possesses unique coloring, stability, and solubility properties
synthesis
the enzyme OKS can be used in the heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans, method, overview