2.3.1.305: acyl-[acyl-carrier protein]�UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose N-acyltransferase

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For detailed information about acyl-[acyl-carrier protein]�UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose N-acyltransferase, go to the full flat file.

Reaction

Synonyms

LpxA

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.305 acyl-[acyl-carrier protein]�UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose N-acyltransferase

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Results	in table
2	AA Sequence
1	Crystallization (Commentary)
3	General Information
16	Natural Substrates/ Products (Substrates)
9	Organism
1	Pathway
1	Reaction
7	Reference
8	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 2.3.1.305 - acyl-[acyl-carrier protein]�UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose N-acyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(3R)-3-hydroxydecanoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxydecanoyl]amino]-alpha-D-glucopyranose

3 entries

(3R)-3-hydroxylauroyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxylauroyl]amino]-alpha-D-glucopyranose

5 entries

(3R)-3-hydroxymyristoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxymyristoyl]amino]-alpha-D-glucopyranose

3 entries

additional information

?

-

5 entries

(3R)-3-hydroxydecanoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxydecanoyl]amino]-alpha-D-glucopyranose

Acidithiobacillus ferrooxidans

Q6QHI7

-

763238

-

-

?

(3R)-3-hydroxydecanoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxydecanoyl]amino]-alpha-D-glucopyranose

Mesorhizobium loti

-

-

763238

-

-

?

(3R)-3-hydroxydecanoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxydecanoyl]amino]-alpha-D-glucopyranose

Mesorhizobium loti ATCC 700743

-

-

763238

-

-

?

(3R)-3-hydroxylauroyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxylauroyl]amino]-alpha-D-glucopyranose

Acidithiobacillus ferrooxidans

Q6QHI7

-

763238

-

-

?

(3R)-3-hydroxylauroyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxylauroyl]amino]-alpha-D-glucopyranose

Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai IPAV

Q8EZA6

-

762720, 763238

-

-

?

(3R)-3-hydroxylauroyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxylauroyl]amino]-alpha-D-glucopyranose

Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai IPAV 56601

Q8EZA6

-

762720, 763238

-

-

?

(3R)-3-hydroxylauroyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxylauroyl]amino]-alpha-D-glucopyranose

Mesorhizobium loti

-

-

763238

-

-

?

(3R)-3-hydroxylauroyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxylauroyl]amino]-alpha-D-glucopyranose

Mesorhizobium loti ATCC 700743

-

-

763238

-

-

?

(3R)-3-hydroxymyristoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxymyristoyl]amino]-alpha-D-glucopyranose

Acidithiobacillus ferrooxidans

Q6QHI7

-

763238

-

-

?

(3R)-3-hydroxymyristoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxymyristoyl]amino]-alpha-D-glucopyranose

Mesorhizobium loti

-

-

763238

-

-

?

(3R)-3-hydroxymyristoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

acyl-carrier protein + UDP-2-acetamido-2,3-dideoxy-3-[[(3R)-3-hydroxymyristoyl]amino]-alpha-D-glucopyranose

Mesorhizobium loti ATCC 700743

-

-

763238

-

-

?

additional information

?

-

Acidithiobacillus ferrooxidans

Q6QHI7

enzyme is also able to accept UDP-N-acetyl-alpha-D-glucosamine, cf. EC 2.3.1.129 and displays relaxed acyl donor chain length selectivity

763238

-

-

-

additional information

?

-

Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai IPAV

Q8EZA6

poor substrates: (3R)-3-hydroxydecanoyl-[acyl-carrier protein], 3-hydroxypalmitoyl-[acyl-carrier protein], (3R)-3-hydroxymyristoyl-[acyl-carrier protein]. Enzyme is highly specific for 2,3-diamino-2,3-dideoxy-D-glucopyranose

763238

-

-

-

additional information

?

-

Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai IPAV 56601

Q8EZA6

poor substrates: (3R)-3-hydroxydecanoyl-[acyl-carrier protein], 3-hydroxypalmitoyl-[acyl-carrier protein], (3R)-3-hydroxymyristoyl-[acyl-carrier protein]. Enzyme is highly specific for 2,3-diamino-2,3-dideoxy-D-glucopyranose

763238

-

-

-

additional information

?

-

Mesorhizobium loti

-

poor substrate: 3-hydroxypalmitoyl-[acyl-carrier protein]

763238

-

-

-

additional information

?

-

Mesorhizobium loti ATCC 700743

-

poor substrate: 3-hydroxypalmitoyl-[acyl-carrier protein]

763238

-

-

-