2.3.1.217: curcumin synthase
This is an abbreviated version!
For detailed information about curcumin synthase, go to the full flat file.
Word Map on EC 2.3.1.217
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2.3.1.217
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curcuma
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diketide-coa
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longa
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curcuminoids
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rhizome
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turmeric
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synthesis
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polyketide
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demethoxycurcumin
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bisdemethoxycurcumin
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ferulic
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4-coumarate
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zingiberaceae
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zedoaria
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condensing
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intraspecies
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caffeoyl-coa
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kwangsiensis
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3-hydroxylase
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analysis
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biofuel production
- 2.3.1.217
- curcuma
-
diketide-coa
- longa
-
curcuminoids
- rhizome
- turmeric
- synthesis
- polyketide
- demethoxycurcumin
- bisdemethoxycurcumin
-
ferulic
- 4-coumarate
-
zingiberaceae
- zedoaria
-
condensing
-
intraspecies
- caffeoyl-coa
- kwangsiensis
-
3-hydroxylase
- analysis
- biofuel production
Reaction
Synonyms
curcumin synthase, curcumin synthase 1, curcumin synthase 2, CURS, CURS1, CURS2, CURS3, OsCUS, ZoCURS
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Natural Substrates Products on EC 2.3.1.217 - curcumin synthase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O
demethoxycurcumin + CO2 + 2 CoA
preferred activity of CURS1, CURS2, and CURS3
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?
feruloyl-CoA + cinnamoyl-diketide-N-acetylcysteamine + H2O
CoA + cinnamoylferuloylmethane + N-acetylcysteamine + CO2
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?
additional information
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CURS1 catalyzes the hydrolysis of diketide-CoA to yield a 2-oxoacid (ii) and decarboxylative condensation of the 2-oxoacid with feruloyl-CoA to yield curcumin
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?
feruloyl-CoA + feruloylacetyl-CoA + H2O
2 CoA + curcumin + CO2
preferred activity of CURS1, CURS2, and CURS3
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?
