2.3.1.181: lipoyl(octanoyl) transferase

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For detailed information about lipoyl(octanoyl) transferase, go to the full flat file.

Reaction

Synonyms

ACP: GcvH octanoyltransferase, ACP:protein-N-octanoyltransferase, At1g47578, At4G31050, AtLIP2p2, bLT, LIP2, LIP2P1, Lip2p2, LIP3, LipB, LipB octanoyltransferase, LipM, lipoate/octanoate transferase, lipoyl (octanoyl)-acyl carrier protein:protein transferase, lipoyl(octanoyl) transferase, lipoyl(octanoyl) transferase 2, lipoyl(octanoyl)-[acyl-carrier-protein]-protein N-lipoyltransferase, lipoyl(octanoyl)transferase, lipoyltransferase, LIPT2, octanoyl (lipoyl): N-octanoyl (lipoyl) transferase, octanoyl-acyl carrier protein:protein-N-octanoyltransferase, octanoyl-[acyl carrier protein {ACP}]:protein N-octanoyltransferase, octanoyl-[acyl carrier protein]-protein N-octanoyltransferase, octanoyl-[acyl carrier protein]:protein N-octanoyltransferase, octanoyltransferase LipM, plastidial octanoyltransferase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.181 lipoyl(octanoyl) transferase

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Results	in table
3	Activating Compound
32527	AA Sequence
2	Application
1	CAS Registry Number
9	Cloned(Commentary)
2	Crystallization (Commentary)
7	Disease/ Diagnostics
23	General Information
1	Inhibitors
3	KM Value [mM]
8	Localization
4	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
28	Organism
8	Pathway
3	pH Optimum
1	pH Range
10	Protein Variants
7	Purification (Commentary)
3	Reaction
2	Reaction Type
26	Reference
4	Source Tissue
1	Specific Activity [micromol/min/mg]
35	Substrates and Products (Substrate)
1	Subunits
56	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Turnover Number [1/s]

Disease

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Disease on EC 2.3.1.181 - lipoyl(octanoyl) transferase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Acidosis, Lactic

Lipoyltransferase 1 Gene Defect Resulting in Fatal Lactic Acidosis in Two Siblings.

27247813

Brain Diseases

Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy.

28757203

Leigh Disease

Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase.

24341803

Mitochondrial Diseases

Progress in the Enzymology of the Mitochondrial Diseases of Lipoic Acid Requiring Enzymes.

32508887

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