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2.3.1.166: 2alpha-hydroxytaxane 2-O-benzoyltransferase

This is an abbreviated version!
For detailed information about 2alpha-hydroxytaxane 2-O-benzoyltransferase, go to the full flat file.

Reaction

benzoyl-CoA
+
10-deacetyl-2-debenzoylbaccatin III
=
CoA
+
10-deacetylbaccatin III

Synonyms

2-O-benzoyltransferase, benzoyl-CoA:taxane 2alpha-O-benzoyltransferase, benzoyltransferase, taxane 2alpha-O-, mTBT, taxane 2alpha-O-benzoyltransferase, TBT

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.166 2alpha-hydroxytaxane 2-O-benzoyltransferase

KCat KM Value

KCat KM Value on EC 2.3.1.166 - 2alpha-hydroxytaxane 2-O-benzoyltransferase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00818
(2alpha,5beta,7beta,10beta,13alpha)-1-hydroxy-9-oxo-5,20-epoxytax-11-ene-2,4,7,10,13-pentayl pentaacetate
reaction was performed with mutant mTBT
0.5782
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl (2E)-but-2-enoate
reaction was performed with mutant mTBT
0.00586
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl 1,3-thiazole-5-carboxylate
reaction was performed with mutant mTBT
0.06371
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl 2-fluorobenzoate
reaction was performed with mutant mTBT
0.00697
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl 2-methylpropanoate
reaction was performed with mutant mTBT
0.00463
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl 3-fluorobenzoate
reaction was performed with mutant mTBT
0.00635
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl 4-chlorobenzoate
reaction was performed with mutant mTBT
0.01056
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl 4-fluorobenzoate
reaction was performed with mutant mTBT
0.00292
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl 4-methylbenzoate
reaction was performed with mutant mTBT
0.0288
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
reaction was performed with mutant mTBT
0.3509
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl butanoate
reaction was performed with mutant mTBT
0.01528
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl furan-2-carboxylate
reaction was performed with mutant mTBT
0.03646
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl furan-3-carboxylate
reaction was performed with mutant mTBT
0.00397
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl hexanoate
reaction was performed with mutant mTBT
0.04858
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl propanoate
reaction was performed with mutant mTBT
0.04815
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl thiophene-2-carboxylate
reaction was performed with mutant mTBT
0.04722
(2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl thiophene-3-carboxylate
reaction was performed with mutant mTBT