2.2.1.9: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
This is an abbreviated version!
For detailed information about 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase, go to the full flat file.
Word Map on EC 2.2.1.9
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2.2.1.9
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menaquinone
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thiamin
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thdp-dependent
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diphosphate-dependent
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alpha-ketoglutarate
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2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic
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dioxide
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benzoylformate
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decarboxylases
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stereoselective
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hydrolases
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alpha/beta
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o-succinylbenzoic
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metal-ion-dependent
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three-domain
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two-stage
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medium-resolution
- 2.2.1.9
- menaquinone
- thiamin
-
thdp-dependent
-
diphosphate-dependent
- alpha-ketoglutarate
-
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic
- dioxide
- benzoylformate
- decarboxylases
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stereoselective
- hydrolases
- alpha/beta
-
o-succinylbenzoic
-
metal-ion-dependent
-
three-domain
-
two-stage
-
medium-resolution
Reaction
Synonyms
(1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, (1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxycyclohex-3-ene-1-carboxylate synthase, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid synthase, EC 2.5.1.64, EcMenD, MenD, Rv0555, SEPHCHC synthase, SHCHC synthase
ECTree
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KM Value
KM Value on EC 2.2.1.9 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
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0.0042
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mutant R293K, pH 7.4, temperature not specified in the publication
0.01
(+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
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mutant R413K, pH 7.4, temperature not specified in the publication
0.012
(+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
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wild-type, pH 7.4, temperature not specified in the publication
0.027
(+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
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mutant I418L, pH 7.4, temperature not specified in the publication
0.036
(+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
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mutant S391A, pH 7.4, temperature not specified in the publication
0.042
(+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
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mutant S32A, pH 7.4, temperature not specified in the publication
0.05
(+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
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mutant R292Q, pH 7.4, temperature not specified in the publication
0.091
(+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
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mutant R107K, pH 7.4, temperature not specified in the publication
0.109
(+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid
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mutant R395K, pH 7.4, temperature not specified in the publication
0.0026
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mutant K292Q, pH 7.4, temperature not specified in the publication
0.0053
2-oxoglutarate
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mutant R107K, pH 7.4, temperature not specified in the publication
0.0091
2-oxoglutarate
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mutant R293K, pH 7.4, temperature not specified in the publication
0.0099
2-oxoglutarate
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wild-type, pH 7.4, temperature not specified in the publication
0.0099
2-oxoglutarate
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mutant S32A, pH 7.4, temperature not specified in the publication
0.012
2-oxoglutarate
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mutant E55D, pH 7.4, temperature not specified in the publication
0.013
2-oxoglutarate
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mutant S391A, pH 7.4, temperature not specified in the publication
0.045
2-oxoglutarate
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mutant R395K, pH 7.4, temperature not specified in the publication
0.2
2-oxoglutarate
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mutant I418L, pH 7.4, temperature not specified in the publication
0.22
2-oxoglutarate
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mutant R413K, pH 7.4, temperature not specified in the publication