2.1.1.365: MMP 1-O-methyltransferase

This is an abbreviated version!
For detailed information about MMP 1-O-methyltransferase, go to the full flat file.

Reaction

Synonyms

3-O-methylmannose polysaccharide 1-O-methyltransferase, MET1, S-adenosyl-L-methionine-dependent sugar 1-O-methyltransferase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.365 MMP 1-O-methyltransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	AA Sequence
1	Cloned(Commentary)
1	Crystallization (Commentary)
1	Inhibitors
3	kcat/KM [mM/s]
4	KM Value [mM]
1	Metals/Ions
2	Natural Substrates/ Products (Substrates)
2	Organism
1	pH Optimum
1	pH Range
6	Protein Variants
1	Purification (Commentary)
1	Reaction
2	Reference
6	Substrates and Products (Substrate)
6	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Systematic Name on EC 2.1.1.365 - MMP 1-O-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

S-adenosyl-L-methionine:3,3'-di-O-methyl-4'-mannobiose 1-O-methyltransferase

Requires Mg2+. The enzyme, characterized from the bacterium Mycolicibacterium hassiacum, participates in the biosynthesis of 3-O-methylmannose polysaccharides (MMP), which are intracellular polymethylated polysaccharides implicated in the modulation of fatty acid metabolism in nontuberculous mycobacteria. The methylation catalysed by this enzyme was shown to block the reducing end of 3,3'-di-O-methyl-alpha-mannobiose, a probable early precursor of the 3-O-methylmannose polysaccharides.