2.1.1.262: squalene methyltransferase
This is an abbreviated version!
For detailed information about squalene methyltransferase, go to the full flat file.
Reaction
2 S-adenosyl-L-methionine + = 2 S-adenosyl-L-homocysteine +
Synonyms
TMT-1, TMT-2, triterpene methyltransferase
ECTree
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Substrates Products
Substrates Products on EC 2.1.1.262 - squalene methyltransferase
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REACTION DIAGRAM
2 S-adenosyl-L-methionine + squalene
2 S-adenosyl-L-homocysteine + 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
S-adenosyl-L-methionine + 3-methyl-1,2-didehydro-2,3-dihydrosqualene
S-adenosyl-L-homocysteine + 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
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-
-
-
?
S-adenosyl-L-methionine + squalene
S-adenosyl-L-homocysteine + 3-methyl-1,2-didehydro-2,3-dihydrosqualene
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-
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-
?
2 S-adenosyl-L-homocysteine + 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
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overall reaction
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-
ir
2 S-adenosyl-L-methionine + squalene
2 S-adenosyl-L-homocysteine + 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
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overall reaction
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-
ir
?
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mono- and dimethylated products with terminal carbon C-3 as the atomic acceptor sites for the methyl additions to squalene, NMR analysis, overview TMT-1 and TMT-2 show only low activity with C30 botryococcene
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?
additional information
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mono- and dimethylated products with terminal carbon C-3 as the atomic acceptor sites for the methyl additions to squalene, NMR analysis, overview TMT-1 and TMT-2 show only low activity with C30 botryococcene
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-
?