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2.1.1.214: tRNA (guanine10-N2)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (guanine10-N2)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.214

Reaction

S-adenosyl-L-methionine
+
guanine10 in tRNA
=
S-adenosyl-L-homocysteine
 +
N2-methylguanine10 in tRNA

Synonyms

(m2G10) methyltransferase, archaeal Trm11, EC 2.1.1.32, eukaryotic m2G10 tRNA methyltransferase, eukaryotic Trm11, N2, N2-dimethylguanosine tRNA methyltransferase, N2,N2-dimethylguanosine tRNA methyltransferase, Tk0981, Trm-G10, Trm-m22G10, Trm11, Trm11-Trm112 complex, Trm11p, Trmp112p, tRNA m2G10/m22G10 methyltransferase, tRNA MTase, YOL124c

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.214 tRNA (guanine10-N2)-methyltransferase

Metals Ions

Metals Ions on EC 2.1.1.214 - tRNA (guanine10-N2)-methyltransferase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Zinc
the enzyme is composed of at least two subunits that are associated in vivo: Trm11p, which is the catalytic subunit, and Trm112p, a putative zinc-binding protein
Zn2+
zinc might be important for Trm11 binding to Trm112, most probably by maintaining the three-dimensional structure of Trm112 zinc-binding domain, which in the other Trm112-MTase complexes is directly interacting with the MTase domains