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1.3.98.6: AdoMet-dependent heme synthase

This is an abbreviated version!
For detailed information about AdoMet-dependent heme synthase, go to the full flat file.

Reaction

Fe-coproporphyrin III
+ 2 S-adenosyl-L-methionine =
protoheme
+ 2 CO2 + 2 5'-deoxyadenosine + 2 L-methionine

Synonyms

ahbD, heme b synthase, Mbar_A1458, SAM-dependent heme synthase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.98 With other, known, physiological acceptors
                1.3.98.6 AdoMet-dependent heme synthase

Reference

Reference on EC 1.3.98.6 - AdoMet-dependent heme synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kühner, M.; Haufschildt, K.; Neumann, A.; Storbeck, S.; Streif, J.; Layer, G.
The alternative route to heme in the methanogenic archaeon Methanosarcina barkeri
Archaea
2014
327637
2014
Methanosarcina barkeri, Methanosarcina barkeri (Q46CH7), Methanosarcina barkeri DSM 804 (Q46CH7)
Manually annotated by BRENDA team
Bali, S.; Lawrence, A.; Lobo, S.; Saraiva, L.; Golding, B.; Palmer, D.; Howard, M.; Ferguson, S.; Warren, M.
Molecular hijacking of siroheme for the synthesis of heme and d1 heme
Proc. Natl. Acad. Sci. USA
108
18260-18265
2011
Desulfovibrio desulfuricans, Desulfovibrio desulfuricans (A0A4P7UJ54)
Manually annotated by BRENDA team
Kuehner, M.; Schweyen, P.; Hoffmann, M.; Ramos, J.; Reijerse, E.; Lubitz, W.; Broering, M.; Layer, G.
The auxiliary [4Fe-4S] cluster of the radical SAM heme synthase from Methanosarcina barkeri is involved in electron transfer
Chem. Sci.
7
4633-4643
2016
Methanosarcina barkeri (Q46CH7), Methanosarcina barkeri DSM 804 (Q46CH7)
Manually annotated by BRENDA team