1.17.2.3: formate dehydrogenase (cytochrome-c-553)

This is an abbreviated version!
For detailed information about formate dehydrogenase (cytochrome-c-553), go to the full flat file.

Reaction

+ 2 ferricytochrome c-553 =

+ 2 ferrocytochrome c-553 +

Synonyms

dehydrogenase, formate (cytochrome), EC 1.2.2.3, FDH, Fdh2, Fdh3, FdhABC3, formate dehydrogenase, formate dehydrogenase (cytochrome)

ECTree

1 Oxidoreductases

1.17 Acting on CH or CH₂ groups

1.17.2 With a cytochrome as acceptor

1.17.2.3 formate dehydrogenase (cytochrome-c-553)

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Results	in table
14	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
1	Expression
2	Inhibitors
3	kcat/KM [mM/s]
4	KM Value [mM]
1	Localization
2	Molecular Weight [Da]
24	Organism
2	Pathway
2	pH Optimum
1	pH Range
10	Protein Variants
5	Purification (Commentary)
1	Reaction
3	Reaction Type
8	Reference
4	Source Tissue
6	Specific Activity [micromol/min/mg]
11	Substrates and Products (Substrate)
11	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
6	Turnover Number [1/s]

Engineering

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Engineering on EC 1.17.2.3 - formate dehydrogenase (cytochrome-c-553)

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Go to Protein Variants Search

K62E

Desulfovibrio vulgaris

mutant of cytochrome c553 per site-directed mutagenesis with 3fold increased initial reaction velocity

288371

K62E/K63E

Desulfovibrio vulgaris

mutant of cytochrome c553 per site-directed mutagenesis with decreased turnover and recognition of the enzyme, but 5fold increased initial reaction velocity

288371

Y64A

Desulfovibrio vulgaris