1.14.14.150: costunolide synthase
This is an abbreviated version!
For detailed information about costunolide synthase, go to the full flat file.
Word Map on EC 1.14.14.150
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1.14.14.150
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sesquiterpene
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germacrene
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lactone
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sunflower
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feverfew
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parthenolide
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asteraceae
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terpene
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planta
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tanacetum
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chicory
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1-deoxy-d-xylulose-5-phosphate
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benthamiana
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synthases
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terpenoids
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reductoisomerase
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trichomes
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parthenium
- 1.14.14.150
-
sesquiterpene
- germacrene
- lactone
- sunflower
- feverfew
- parthenolide
- asteraceae
-
terpene
-
planta
-
tanacetum
- chicory
- 1-deoxy-d-xylulose-5-phosphate
- benthamiana
- synthases
-
terpenoids
- reductoisomerase
-
trichomes
- parthenium
Reaction
Synonyms
(+)-costunolide synthase, CcaCOS, COS, CYP71BL1, CYP71BL2, CYP71BL3, CYP71Bl5, CYP71BL9, EC 1.14.13.120
ECTree
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Reference on EC 1.14.14.150 - costunolide synthase
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
de Kraker, J.W.; Franssen, M.C.R.; Joerink, M.; de Groot, A.; Bouwmeester, H.J.
Biosynthesis of costunolide, dihydrocostunolide, and leucodin. Demostration of cytochrome P450-catalyzed formation of the lactone ring present in sesquiterpene lactones of chicory
Plant Physiol.
129
257-268
2002
Cichorium intybus
Ikezawa, N.; Goepfert, J.C.; Nguyen, D.T.; Kim, S.U.; OMaille, P.E.; Spring, O.; Ro, D.K.
Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism
J. Biol. Chem.
286
21601-21611
2011
Helianthus annuus, Lactuca sativa (F8S1I0)
Liu, Q.; Majdi, M.; Cankar, K.; Goedbloed, M.; Charnikhova, T.; Verstappen, F.W.; de Vos, R.C.; Beekwilder, J.; van der Krol, S.; Bouwmeester, H.J.
Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana
PLoS ONE
6
e23255
2011
Cichorium intybus (G3GBK0), Cichorium intybus
Farzadfar, S.; Zarinkamar, F.; Behmanesh, M.; Hojati, M.
Magnesium and manganese interactively modulate parthenolide accumulation and the antioxidant defense system in the leaves of Tanacetum parthenium
J. Plant Physiol.
202
10-20
2016
Tanacetum parthenium
Eljounaidi, K.; Cankar, K.; Comino, C.; Moglia, A.; Hehn, A.; Bourgaud, F.; Bouwmeester, H.; Menin, B.; Lanteri, S.; Beekwilder, J.
Cytochrome P450s from Cynara cardunculus L. CYP71AV9 and CYP71BL5, catalyze distinct hydroxylations in the sesquiterpene lactone biosynthetic pathway
Plant Sci.
223
59-68
2014
Cynara cardunculus var. altilis (A0A059WMF6), Cynara cardunculus var. altilis
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