1.14.11.B22: ergot alkaloid dioxygenase

This is an abbreviated version!
For detailed information about ergot alkaloid dioxygenase, go to the full flat file.

Reaction

Synonyms

EasH

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

                1.14.11.B22 ergot alkaloid dioxygenase

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1	AA Sequence
1	Cloned(Commentary)
2	General Information
1	Metals/Ions
1	Organism
1	Reaction
1	Reference
3	Substrates and Products (Substrate)
1	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 1.14.11.B22 - ergot alkaloid dioxygenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

9,10-dihydrolysergol + 2-oxoglutarate + O2

8beta-(hydroxymethyl)-6-methylergolin-4-ol + succinate + CO2 + H2O

Aspergillus japonicus

A0A1L1QK38

-

764001

-

-

?

elymoclavine + 2-oxoglutarate + O2

8-(hydroxymethyl)-6-methyl-8,9-didehydroergolin-4-ol + succinate + CO2 + H2O

Aspergillus japonicus

A0A1L1QK38

-

764001

-

-

?

festuclavine + 2-oxoglutarate + O2

6,8beta-dimethylergolin-4-ol + succinate + CO2 + H2O

Aspergillus japonicus

A0A1L1QK38

asymmetric hydroxylation at the C-4 position of ergot alkaloid festuclavine

764001

-

-

?