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1.1.98.7: Ser-type anaerobic sulfatase-maturating enzyme

This is an abbreviated version!
For detailed information about Ser-type anaerobic sulfatase-maturating enzyme, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
a [sulfatase]-L-serine
=
a [sulfatase]-3-oxo-L-alanine
 +
5'-deoxyadenosine
 +
L-methionine

Synonyms

anaerobic sulfatase-maturating enzyme, anSME, AtsB, cpe0635, nSMEcpe, Ser-type anaerobic sulfatase-maturating enzyme

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.98 With other, known, physiological acceptors
                1.1.98.7 Ser-type anaerobic sulfatase-maturating enzyme

Natural Substrates Products

Natural Substrates Products on EC 1.1.98.7 - Ser-type anaerobic sulfatase-maturating enzyme

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + a [Klebsiella pneumoniae sulfatase]-L-serine
[Klebsiella pneumoniae sulfatase]-3-oxo-L-alanine + 5'-deoxyadenosine + L-methionine
show the reaction diagram
the atsB gene product plays a posttranslational role that is essential for the sulfatase to gain its catalytic activity
-
-
?
S-adenosyl-L-methionine + a [sulfatase]-L-serine
a [sulfatase]-3-oxo-L-alanine + 5'-deoxyadenosine + L-methionine
show the reaction diagram
S-adenosyl-L-methionine + [periplasmic sulfatase AtsA]-L-serine
[periplasmic sulfatase AtsA]-3-oxo-L-alanine + 5'-deoxyadenosine + L-methionine
show the reaction diagram
the enzyme is strictly required for modification of Ser72 in the periplasmic sulfatase AtsA of Klebsiella pneumoniae. AtsB-mediated formation of 3-oxo-L-alanine is dependent on the signal peptide of AtsA
-
-
?