1.1.1.427: D-arabinose 1-dehydrogenase (NADP+)
This is an abbreviated version!
For detailed information about D-arabinose 1-dehydrogenase (NADP+), go to the full flat file.
Reaction
Synonyms
adh-4, ARA, ARA1, Ara1p, AraDH, D-arabinose dehydrogenase, NADP(+)-dependent D-arabinose dehydrogenase, Sso1300
ECTree
1.1.1.427 D-arabinose 1-dehydrogenase (NADP+)Advanced search results
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results (Substrates Products
Substrates Products on EC 1.1.1.427 - D-arabinose 1-dehydrogenase (NADP+)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(R/S)-acetoin + NADPH
(2S,3S)-2,3-butanediol + NADP+
-
Ara1p is as an oxidoreductase that can reduce racemic acetoin to meso-2,3-butanediol and (2S,3S)-2,3-butanediol in the presence of NADPH
-
-
?
L-fucose + NADP+
6-deoxy-L-galactono-1,4-lactone + NADPH + H+
-
-
-
?
L-galactose + NADP+
L-galactonolactone + NADPH
-
-
-
?
2,3-pentanedione + NADPH + H+
hydroxypentanone + NADP+
-
-
-
-
?
acetoin + NADP+
diacetyl + NADPH + H+
-
this back reaction only occurs at alkaline pH values (9.0-10.0)
-
-
r
acetoin + NADP+
diacetyl + NADPH + H+
-
this back reaction only occurs at alkaline pH values (9.0-10.0)
-
-
r
D-arabinose + NAD+
D-arabinono-1,4-lactone + NADH + H+
-
-
-
?
D-arabinose + NAD+
D-arabinono-1,4-lactone + NADH + H+
-
-
-
?
D-arabinose + NADP+
D-arabinono-1,4-1actone + NADPH + H+
-
-
-
-
?
D-arabinose + NADP+
D-arabinono-1,4-1actone + NADPH + H+
-
-
-
-
?
D-arabinose + NADP+
D-arabinono-1,4-lactone + NADPH + H+
-
-
-
?
D-arabinose + NADP+
D-arabinono-1,4-lactone + NADPH + H+
the enzyme is involved in the conversion of D-arabinose into the tricarboxylic acid cycle intermediate 2-oxoglutarate via the pentose oxidation pathway
-
-
?
D-arabinose + NADP+
D-arabinono-1,4-lactone + NADPH + H+
-
-
-
?
D-arabinose + NADP+
D-arabinono-1,4-lactone + NADPH + H+
the enzyme is involved in the conversion of D-arabinose into the tricarboxylic acid cycle intermediate 2-oxoglutarate via the pentose oxidation pathway
-
-
?
D-arabinose + NADP+
D-arabinono-1,4-lactone + NADPH + H+
-
-
-
?
L-fucose + NADP+
L-fuconolactone + NADPH + H+
most active with L-fucose as substrate
-
-
?
L-fucose + NADP+
L-fuconolactone + NADPH + H+
most active with L-fucose as substrate
-
-
?
additional information
?
-
the enzyme is specific for sugars with D-arabinose-type hydroxyl group stereo-configurations at C3 and C4. Negligible activity with D-glucose, D-galactose, D-fucose, L-arabinose and D-xylose
-
-
?
additional information
?
-
the enzyme is specific for sugars with D-arabinose-type hydroxyl group stereo-configurations at C3 and C4. Negligible activity with D-glucose, D-galactose, D-fucose, L-arabinose and D-xylose
-
-
?
additional information
?
-
-
enzyme in addition acts as a NADPH-dependent oxidoreductase producing meso-2,3-butanediol and (2S,3S)-2,3-butanediol from (R,S)-acetoin
-
-
?
additional information
?
-
-
the recombinant subunit ARA1p shows 0.5% activity with NAD+ compared to NADPH and has no activity with glycerol
-
-
-
additional information
?
-
-
the recombinant subunit ARA1p shows 0.5% activity with NAD+ compared to NADPH and has no activity with glycerol
-
-
-
