EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    1.1.1.205 | -999 |
- |
more |
the inhibitors all exhibit inhibitory potencies with IC50 values of over 0.005 mM with wild-type and truncation mutant |
740742 |
| 1.1.1.205 | 0.0000005 |
- |
(2S)-2-[(3,4-dichlorophenyl)amino]-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]propanamide |
pH 8.0, 25°C |
725678 |
| 1.1.1.205 | 0.00000066 |
- |
1-(4-chloro-5-nitrocyclohexa-1,5-dien-1-yl)-3-(2-[3-[(1E)-N-hydroxyethanimidoyl]phenyl]propan-2-yl)urea |
pH 8.0, 25°C |
725673 |
| 1.1.1.205 | 0.0000008 |
- |
1-[2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl]-3-quinolin-7-ylurea |
pH 8.0, 25°C |
725673 |
| 1.1.1.205 | 0.0000009 |
- |
1-(2-[3-[(1E)-N-hydroxyethanimidoyl]phenyl]propan-2-yl)-3-quinolin-7-ylurea |
pH 8.0, 25°C |
725673 |
| 1.1.1.205 | 0.000001 |
- |
thiazole-4-carboxamide 2-ethyladenine dinucleotide |
pH 8.0, 25°C |
711475 |
| 1.1.1.205 | 0.0000011 |
- |
N-(naphthalen-2-yl)-2-[2-(pyridin-2-yl)-5,6-dihydro-1H-benzimidazol-1-yl]acetamide |
pH 8.0, 25°C |
711735 |
| 1.1.1.205 | 0.0000019 |
- |
N-(naphthalen-2-yl)-2-[2-(pyridin-2-yl)-5,6-dihydro-1H-benzimidazol-1-yl]acetamide |
mutant S250A/L444Y, pH 8.0, 25°C |
711735 |
| 1.1.1.205 | 0.000002 |
- |
2-[(3,4-dichlorophenyl)amino]-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]propanamide |
pH 8.0, 25°C |
725678 |
| 1.1.1.205 | 0.0000021 |
- |
N-naphthalen-2-yl-N'-[2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl]urea |
pH and temperature not specified in the publication |
761804 |
