EC Number   |
pH Optimum Minimum |
pH Optimum Maximum |
Reference |
|---|
    1.5.1.3 | -999 |
- |
- |
392224 |
| 1.5.1.3 | -999 |
- |
enzyme-dihydrofolate complex is soluble at basic pH and precipitates reversibly at acidic pH |
392295 |
| 1.5.1.3 | -999 |
- |
overview |
392224, 392290 |
| 1.5.1.3 | -999 |
- |
trimethoprim-resistant, form 2: no detectable pH-optimum, continuous increase of activity as pH decreases from pH 9.0 to pH 4.0 |
392239 |
| 1.5.1.3 | 3.8 |
- |
folate + NADPH |
392274 |
| 1.5.1.3 | 4 |
- |
3 optima: pH 4.0, pH 7.3-7.5 and pH 8.3-8.5 |
392273 |
| 1.5.1.3 | 4 |
- |
7,8-dihydrofolate + NADPH, 2 optima: pH 4 and pH 7.4 |
392208, 392274 |
| 1.5.1.3 | 4 |
- |
human WIL 2 cell line, 2 optima: pH 4 and pH 7.3-8.3 |
392208 |
| 1.5.1.3 | 4 |
- |
isozyme hDHFR-1 |
392284 |
| 1.5.1.3 | 4 |
- |
methotrexate resistant cells L1210 (R), sarcoma 180 (AT/300), 2 optima: pH 4 and pH 7.5 |
392208 |
