EC Number   |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
|---|
   1.1.1.62 | 0.00028 |
- |
5-androstene-3beta,17beta-diol |
17beta-HSD14 variant S205, pH and temperature not specified in the publication |
740849 |
| 1.1.1.62 | 0.00032 |
- |
5-androstene-3beta,17beta-diol |
17beta-HSD14 variant T205, pH and temperature not specified in the publication |
740849 |
| 1.1.1.62 | 0.0004 |
- |
17beta-estradiol |
17beta-HSD14 variant S205, pH and temperature not specified in the publication |
740849 |
| 1.1.1.62 | 0.00055 |
- |
17beta-estradiol |
17beta-HSD14 variant T205, pH and temperature not specified in the publication |
740849 |
| 1.1.1.62 | 0.0063 |
- |
estrone |
pH 7.5, 37°C |
761756 |
| 1.1.1.62 | 0.011 |
- |
17beta-estradiol |
pH and temperature not specified in the publication |
760700 |
| 1.1.1.62 | 0.0153 |
- |
5alpha-dihydrotestosterone |
pH 7.5, 37°C |
761756 |
| 1.1.1.62 | 0.065 |
- |
NADPH |
25°C, pH 8.0, mutant enzyme Y49D, cosubstrate: 4-estrene-3,17-dione |
687869 |
| 1.1.1.62 | 0.1 |
- |
allopregnanolone |
pH and temperature not specified in the publication |
760700 |
| 1.1.1.62 | 0.12 |
- |
dehydroepiandrosterone |
mutant enzyme L149V |
670265 |
