EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.3.1.61 | more |
the DLST gene is bifunctionally involved in mitochondrial energy metabolism, the full-length DLST protein is involved in the Krebs cycle and the truncated version, MIRTD, contributes to the biogenesis of the respiratory chain. The genotype of the DLST gene is associated with Alztheimers disease without a change of amino acid residues in the DLST protein: through a decrease in the expression of the truncated gene product MIRTD and the function of MIRTD. It remains unclear how much MIRTD actually contributes to the pathogenesis of Alzheimers disease |
Homo sapiens |
? |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Haemophilus influenzae |
CoA + S-succinyldihydrolipoamide |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Bacillus subtilis |
CoA + S-succinyldihydrolipoamide |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Escherichia coli |
CoA + S-succinyldihydrolipoamide |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Homo sapiens |
CoA + S-succinyldihydrolipoamide |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Rattus norvegicus |
CoA + S-succinyldihydrolipoamide |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Sus scrofa |
CoA + S-succinyldihydrolipoamide |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Saccharomyces cerevisiae |
CoA + S-succinyldihydrolipoamide |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Bos taurus |
CoA + S-succinyldihydrolipoamide |
- |
? |
2.3.1.61 | succinyl-CoA + dihydrolipoamide |
- |
Geobacillus stearothermophilus |
CoA + S-succinyldihydrolipoamide |
- |
? |