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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.206more Trm56 and an yet unknown tRNA (m7G49) methyltransferase might be included in protein complexes and precipitated by centrifugation at 30000 × g. Thermoplasma acidophilum Trm56 might be part of a large complex with other proteins in living cells -, 756985
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.206physiological function the enzyme Trm56 is responsible for the typical archaeal tRNA modification of 2'-O-methylcytidine at position 56 (Cm56). The Cm modification is only found at position 56 in native tRNALeuUAG. Trm56 methylates both the elongator tRNAMet transcript and its precursor. But the methyl group acceptance activity of the precursor is considerably lower than that of the mature transcript, the methylation by Trm56 occurs mainly after the removal of the intron -, 756985
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