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EC Number	General Information	Commentary	Reference
2.1.1.106	physiological function	TsrM can catalyze multiple turnovers in the absence of any reducing agent, but only when it is pre-loaded with methylcobalamin. When hydroxocobalamin or cob(II)alamin is bound to TsrM, a reductant is required to convert it to cob(I)alamin, which can acquire a methyl group directly from S-adenosylmethionine. TrsM is most active when flavodoxin/flavodoxin reductase/NADPH is included in the reaction	757245

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Release 2023.1 (January 2023)