EC Number   |
Expression |
Reference |
|---|
    2.4.1.17 | down |
all-trans-retinoic acid appears to downregulate UGT2B7 expression |
735649 |
| 2.4.1.17 | up |
bilirubin and 20-hydroxyeicosatetraenoic acid act as activators of transcription factors that regulate UGT expression, and are involved in important feedback loops |
735649 |
| 2.4.1.17 | up |
bilirubin and 20-hydroxyeicosatetraenoic acid act as activators of transcription factors that regulate UGT expression, and are involved in important feedback loops. Induction of UGT1A1 in keratinocytes by UV radiation-generated 6-formylindolo[3,2-b]carbazole, which is a potent activator of AhR transcription factor. Induction of UGT1A1 in the neonatal period is controlled in part by a cluster of 6 transcription factor response elements, termed gtPBREM (phenobarbital-responsive enhancer module) binding CAR, PXR, AhR, NRF2, PPARa and glucocorticoid receptor |
735649 |
| 2.4.1.17 | up |
bilirubin and 20-hydroxyeicosatetraenoic acid act as activators of transcription factors that regulate UGT expression, and are involved in important feedback loops. Intestinal UGT1A6 expression and serotonin glucuronidation is induced by activation of the AhR and Nrf2, the genetically-linked master regulator of the antioxidant response |
735649 |
| 2.4.1.17 | up |
there is a significant increase in the expression of isoform UGT1A1 during the first 25 years of life |
756805 |
| 2.4.1.17 | up |
there is a significant increase in the expression of isoform UGT1A3 during the first 25 years of life |
756805 |
| 2.4.1.17 | up |
there is a significant increase in the expression of isoform UGT1A4 during the first 25 years of life |
756805 |
| 2.4.1.17 | up |
there is a significant increase in the expression of isoform UGT1A5 during the first 25 years of life |
756805 |
| 2.4.1.17 | up |
there is a significant increase in the expression of isoform UGT1A6 during the first 25 years of life |
756805 |
| 2.4.1.17 | up |
there is a significant increase in the expression of isoform UGT2B17 during the first 25 years of life |
756805 |
