EC Number |
Expression |
Reference |
---|
1.3.1.22 | more |
androgen regulates the mRNA level of 5alpha reductase isoenzymes in a cell type-specific manner. Regulation occurs at the transcriptional level, and the androgen receptor is necessary for this regulation |
726288 |
1.3.1.22 | more |
androgen regulates the mRNA level of 5alpha reductase isoenzymes in a cell type-specific manner. Regulation occurs at the transcriptional level, and the androgen receptor is necessary for this regulation. The androgen receptor is recruited to a negative androgen response element on the promoter of isoform SRD5A3 in vivo and directly binds to the negative androgen response element in vitro |
726288 |
1.3.1.22 | up |
morphine significantly reduces the testosterone concentration after acute and chronic exposure in the spinal cord. In contrast, the 5alpha-reductase 1 expression and of course dihydrotestosterone levels increase the following chronic morphine administration |
726046 |
1.3.1.22 | up |
transcription and expression levels of both 5alpha-reductase isozymes were significantly higher in environmentally stressed rats than in unstressed rats |
726043 |