EC Number   |
Natural Substrates |
|---|
   2.3.1.42 | acyl-CoA + glycerone phosphate |
- |
| 2.3.1.42 | dihydroxyacetone phosphate + acyl-CoA |
- |
| 2.3.1.42 | palmitoyl-CoA + dihydroxyacetone phosphate |
- |
| 2.3.1.42 | more |
enzyme activity is reduced with disorders: neonatal adrenoleukodystrophy, infantile Refsum disease, and hyperpipecolic acidemia |
| 2.3.1.42 | more |
enzyme amount is reduced by 90% in Zellweger syndrome |
| 2.3.1.42 | acyl-CoA + glycerone phosphate |
enzyme is essential for biosynthesis of plasmalogens and nonetherlipids, the peroxisomal isozymes does not contribute to nonetherlipid biosynthesis |
| 2.3.1.42 | acyl-CoA + glycerone phosphate |
enzyme is involved in biosynthesis of plasmalogens, regulating enzyme |
| 2.3.1.42 | palmitoyl-CoA + dihydroxyacetone phosphate |
initiates glycerolipid, especially ether-linked glycerolipid, biosynthesis in higher eukaryotes |
| 2.3.1.42 | palmitoyl-CoA + dihydroxyacetone phosphate |
no precursor for glycerol ether lipids |
| 2.3.1.42 | palmitoyl-CoA + dihydroxyacetone phosphate |
obligate precursor in ether lipids biosynthesis |
