EC Number |
Inhibitors |
Structure |
---|
3.5.1.6 | (R)-2-phenylpropionic acid |
IC50: 0.115 mM |
|
3.5.1.6 | (RS)-2-(2,6-dinitrophenoxy)-propionate |
most potent inhibitor of aryl propionates, IC50: 500 nM, completely reversible by passing the enzyme-inhibitor complex over a gel filtration column |
|
3.5.1.6 | (RS)-2-benzylpropionic acid |
IC50: 0.006 mM |
|
3.5.1.6 | (S)-2-phenylpropionic acid |
IC50: 0.0057 mM |
|
3.5.1.6 | 1,10-phenanthroline |
1 mM, 96% inhibition, activity can be partially restored by Zn2+ |
|
3.5.1.6 | 2,2'-dipyridyl |
2 mM 70% inhibition |
|
3.5.1.6 | 2,6-dipicolinic acid |
1 mM, 33% inhibition |
|
3.5.1.6 | 2-methyl-beta-alanine |
product inhibition, the presence of product leads to dissociation of hexamers to inactive trimers |
|
3.5.1.6 | 2-methyl-N-carbamoyl-beta-alanine |
competitive inhibitor of the reaction with N-carbamoyl-beta-alanine |
|
3.5.1.6 | 3-Phenylpropionic acid |
IC50: 0.0056 mM |
|