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Literature summary extracted from

  • Gonzalez, E.; Fernandez, M.R.; Larroy, C.; Pares, X.; Biosca, J.A.
    Characterization and functional role of Saccharomyces cerevisiae 2,3-butanediol dehydrogenase (2001), Chem. Biol. Interact., 130, 425-434.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.4 overexpression in Saccharomyces cerevisiae Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.4 4-Methylpyrazole
-
 Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.4 0.055
-
 NADH
-
 Saccharomyces cerevisiae
1.1.1.4 0.55
-
 NAD+
-
 Saccharomyces cerevisiae
1.1.1.4 4.5
-
 (3R,3S)-acetoin
-
 Saccharomyces cerevisiae
1.1.1.4 14
-
 (2R,3R)-2,3-butanediol
-
 Saccharomyces cerevisiae
1.1.1.4 14.5
-
 1-hydroxy-2-propanone
-
 Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.4 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.4
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.4 (2R,3R)-2,3-butanediol + NAD+
-
 Saccharomyces cerevisiae (3R)-acetoin + NADH
-
 r
1.1.1.4 (3R,3S)-acetoin + NADH
-
 Saccharomyces cerevisiae (2R,3R)-2,3-butanediol + meso-2,3-butanediol + NAD+
-
 r
1.1.1.4 1-hydroxy-2-propanone + NADH + H+
-
 Saccharomyces cerevisiae propane-1,2-diol + NAD+
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.4 7 8
-
 Saccharomyces cerevisiae

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.4 5 9
-
 Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.4 NAD+ no activity with NADP+ as cofactor Saccharomyces cerevisiae