Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the urea cycle enzyme CPS1 is the antigen for Hep Par 1 antibody | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
166000 | - |
mass spectrometry | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NH3 + CO2 + H2O | Homo sapiens | CPS1 is a rate-limiting enzyme in the urea cycle | ADP + phosphate + carbamoyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Hep-G2 cell | hepatocarcinoma cell line, suppression of CPS1 expression occurs at the transcriptional level | Homo sapiens | - |
hepatoma cell | hepatoid tumors of gastric and yolk sac | Homo sapiens | - |
Huh-7 cell | hepatocarcinoma cell line, suppression of CPS1 expression occurs at the transcriptional level | Homo sapiens | - |
LH-86 cell | hepatocarcinoma cell line, suppression of CPS1 expression occurs at the transcriptional level | Homo sapiens | - |
liver | - |
Homo sapiens | - |
additional information | no expression in gallbladder, thyroid, spleen, kidney, and skin, immunohistochemic analysis, overview, CPS1 expression is suppressed at the transcriptional level in human hepatocellular carcinoma cell lines | Homo sapiens | - |
small intestine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NH3 + CO2 + H2O | - |
Homo sapiens | ADP + phosphate + carbamoyl phosphate | - |
? | |
ATP + NH3 + CO2 + H2O | CPS1 is a rate-limiting enzyme in the urea cycle | Homo sapiens | ADP + phosphate + carbamoyl phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carbamoyl phosphate synthetase 1 | - |
Homo sapiens |
CPS1 | - |
Homo sapiens |
p165 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | sequence calculation | - |
6.3 |