Application | Comment | Organism |
---|---|---|
biotechnology | ammonia elimination as functional marker in hepatocyte cultivation and zonation in a bioreactor, and construction of a bioartificial liver, overview | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Sus scrofa | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NH3 + CO2 + H2O | Sus scrofa | CPS is the rate-determining enzyme of the urea cycle and catalyzes the conversion of ammonia and bicarbonate to carbamoylphosphate in the periportal and intermediate zones of a liver lobule, overview. The enzyme is responsible for ammonia elimination | ADP + phosphate + carbamoyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatocyte | - |
Sus scrofa | - |
liver | dynamic expression pattern of the enzyme in hepatocytes of different zones of the liver lobule, overview | Sus scrofa | - |
additional information | mechanism underlying metabolic zonation, overview | Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NH3 + CO2 + H2O | - |
Sus scrofa | ADP + phosphate + carbamoyl phosphate | - |
? | |
ATP + NH3 + CO2 + H2O | CPS is the rate-determining enzyme of the urea cycle and catalyzes the conversion of ammonia and bicarbonate to carbamoylphosphate in the periportal and intermediate zones of a liver lobule, overview. The enzyme is responsible for ammonia elimination | Sus scrofa | ADP + phosphate + carbamoyl phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CPS | - |
Sus scrofa |
mitochondrial carbamoylphosphate synthetase I | - |
Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Sus scrofa |